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Efficacy of 7f (1, 3, 10, 30 mg/kg) or prednisolone (10 mg/kg) vs vehicle in a MRL/lpr mouse model of lupus showing changes to proteinuria levels (A), anti-dsDNA antibody titer (B), and plasma IL-10 (C). *p < 0.05, **p < 0.01, ***p < 0.001. One-way ANOVA with Dunnett’s test compared to the vehicle. N = 12 mice per group.
