Table 2.
Change from baseline in adapted SH and Poznanski scores
| Score | Baseline | Change from baseline to week 52 | Change from baseline to week 104 | |||||
|---|---|---|---|---|---|---|---|---|
| n | Median (IQR) | n | Median (IQR) | P | n | Median (IQR) | P | |
| sJIA | ||||||||
| Adapted total SH | 47 | 24.60 (8.50, 39.50) | 45 | 0.00 (− 8.70, 4.00) | 0.302 | 37 | 0.50 (− 7.50, 12.00) | 0.695 |
| Erosion | 47 | 8.50 (1.50, 23.50) | 45 | 0.50 (− 3.50, 1.50) | 0.677 | 37 | 0.50 (− 1.00, 4.50) | 0.257 |
| JSN | 47 | 13.00 (6.00, 19.50) | 45 | 0.00 (− 4.00, 3.00) | 0.257 | 37 | 0.00 (− 5.50, 4.00) | 0.937 |
| Poznanski | 33 | − 2.38 (− 3.48, − 0.84) | 32 | 0.29 (− 0.05, 1.05) | 0.003 | 26 | 0.16 (− 0.01, 1.04) | 0.057 |
| pcJIA | ||||||||
| Adapted total SH | 45 | 8.00 (3.00, 18.50) | 40 | 0.50 (− 7.25, 4.50) | 0.700 | 35 | − 1.00 (− 6.50, 2.50) | 0.109 |
| Erosion | 45 | 3.00 (0.00, 6.50) | 40 | 0.00 (− 1.50, 1.50) | 0.819 | 36 | 0.00 (− 2.75, 0.75) | 0.402 |
| JSN | 45 | 5.00 (1.00, 14.50) | 40 | 0.25 (− 5.25, 3.50) | 0.614 | 35 | − 1.00 (− 3.50, 1.50) | 0.109 |
| Poznanski | 35 | − 1.45 (− 2.51, − 0.75) | 31 | 0.26 (− 0.34, 0.91) | 0.077 | 25 | 0.55 (0.04, 0.92) | 0.004 |
Abbreviations: IQR interquartile range, JSN joint space narrowing, pcJIA polyarticular-course juvenile idiopathic arthritis, SH Sharp–van der Heijde, sJIA systemic juvenile idiopathic arthritis
SH score: higher score indicates greater damage. Poznanski score: the more negative a Poznanski score, the more severe the radiographic damage