Table 3.

MiRNA regulation during obesity, their function in the cardiovascular system and their potential targets in the redox system

miRNA	Up/downregulation (obesity)	Refs.	Function	Refs.	Target	Refs.
miR-210	Unknown	–	EC apoptosis and atherosclerosis	[125]	ISCU 1,2	[124]
miR-21	Up	[130, 131]	Promotes ROS production	[132, 133]	SOD	[132, 133]
miR-551b	Up	[ [140]	Enhances ROS accumulation	[134, 135]	CAT, SOD	[134, 135]
miR-200c	Up	[142, 143]	EC apoptosis, ROS accumulation and senescence	[144, 145]	PRDX2	[144]
miR-17	Up	[151, 152]	EC dysfunction	[151, 152]	SOD, Gpx2	[149]
miR-23b	Up	[148]	EC dysfunction	[52, 146]	PRDX3	[147]
miR-29	Up	[154]	EC dysfunction, Cellular senescence	[155, 156]	ROS	[153]
miR-448	Down	[162, 163]	Attenuation of NOX2 induced-ROS accumulation	[161]	NOX2	[161]
miR-19b	Down	[166]	Attenuation of inflammation-induced EC apoptosis	[165]	p47phox	[164]
miR-25	Down	[170]	Prevent ROS production	[170]	NOX4	[170]
miR-146a	Up	[174]	EC inflammation	[173]	NOX4	[173]