Figure 7.

Study of phenotypic shift in vivo. Immunofluorescence and quantitative analysis of CD206 (A) and (B) and INOS (C) and (D) expression on sectioned plaque collected after treatment (mean ± SD, n = 3, ∗P < 0.05 and ∗∗∗P < 0.001). The nuclei were stained with DAPI (blue) and CD206 and INOS were stained with Alexa Fluor 488-conjugated antibody (green). The scale bar is 100 μm. The formulations were injected into the animals via the tail vein every 3 days at a baicalein dose of 5 mg/kg, anti-miR 155 dose of 0.2 mg/kg, or atorvastatin dose of 1 mg/kg, according to the body weight.