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. 2019 Dec 16;10(8):1476–1491. doi: 10.1016/j.apsb.2019.12.008

Figure 6.

Figure 6

Compound 19 inhibited colony formation and proliferation of gastric cancer cells. (A) Colony formation inhibition of HGC-27 and MGC-803 by compound 19 was determined by crystal violet after 8 days treatment. (B) Quantitative analysis of the colony number. (C) Colonies were stained with crystal violet after USP28 knockdown with siRNA for 48 h in HGC-27. (D) Quantitative analysis of the colony number. (E) DNA proliferation in HGC-27 cells after treatment with compound 19 was determined by confocal laser scanning microscope after 8 days treatment. ∗∗P < 0.05 and ∗∗P < 0.01 were considered significant. Data are the mean ± standard deviation (SD). All experiments were performed for three times.