Table 5. Exposure of Compound 20 across Species (n = 3).

Species	Route	Dose(mg/kg)	Tmax (h)	Cmax(ng/mL)	t1/2 (h)	Vss(L/kg)	CLb(mL/min/kg)	F (%)
Rat	IV	0.5			0.8	2	39
	Oral	3	0.5	226				43
Dog	IV	0.5			2.2	2	12
	Oral	3	0.75	705				57
Monkey	IV	0.5			5	2	5
	Oral	3	2	730				42