Table 2.
Demographic and clinical characteristics of subset participants with PET data
| Non-carriers (n = 35) | Cognitively intact carriers (n = 19) | Symptomatic carriers (n = 12) | |
|---|---|---|---|
| M (SD) | |||
| Demographic and clinical variables | |||
| Age (years) | 34.69 (4.84) | 33.95 (5.08) | 42.25 (3.41) |
| Education (years) | 11.03 (4.16) | 11.21 (3.15) | 5.75 (3.14) |
| MMSE | 28.97 (.92) | 28.68 (.88) | 25.08 (3.23) |
| GDS | .94 (1.49) | .63 (1.46) | 2.75 (3.22) |
| Cognitive variables | |||
| CERAD Word List Learning | 20.91 (3.15) | 20.05 (2.99) | 12.50 (3.87) |
| CERAD Word List Delayed Recall | 7.69 (1.25) | 7.05 (1.96) | 2.92 (2.39) |
| CERAD Word List Recognition | 9.74 (.56) | 9.84 (.37) | 7.33 (2.27) |
| CERAD CP- Copy | 10.40 (1.03) | 10.58 (.61) | 9.50 (1.31) |
| CERAD CP- Delayed Recall | 9.51 (1.58) | 10.05 (1.58) | 3.83 (3.43) |
| Phonemic Fluency (FAS) | 32.54 (7.69) | 36.74 (7.96) | 29.17 (8.40) |
| Semantic Fluency (Animals) | 20.00 (3.66) | 21.68 (4.70) | 18.25 (3.93) |
| Boston Naming Test (BNT-15) | 13.86 (1.00) | 13.58 (1.17) | 13.00 (1.76) |
Note: Symptomatic carriers include participants with FAST scores of 2 and 3 indicating presence of SCD concerns and MCI, respectively
Abbreviations: M mean, SD standard deviation, FAST Functional Assessment Staging test, MMSE Mini Mental State Exam, GDS Geriatric Depression Scale, CERAD Consortium to Establish a Registry for Alzheimer’s Disease, CP constructional praxis