. 2020 Sep 11;20:275. doi: 10.1186/s12906-020-03070-8

Table 2.

Effects of the leaf aqueous extract of M. arboreus on ovarian follicle growth and maturation

Groups	Primary follicles	Secondary follicles	Tertiary follicles	Graafian follicles	Corpora lutea	Cystic follicles	Atretic follicles
NC	3.20 ± 0.49	2.80 ± 0.20	2.20 ± 0.37	2.40 ± 0.24	12.00 ± 1.26	0.00 ± 0.00	5.60 ± 0.51
LTZ	1.50 ± 0.22^*	0.80 ± 0.37	1.40 ± 0.24	1.60 ± 0.24	4.75 ± 0.19^***	13.25 ± 0.79^***	10.60 ± 0.60^***
LTZ + CC + MET	5.00 ± 0.32^{*, ###}	4.75 ± 0.37^#	6.00 ± 0.45^{***, ###}	3.80 ± 0.58^##	10.00 ± 1.14^###	2.33 ± 0.18^{**, ###}	7.00 ± 0.45 ^###
LTZ + AE 20	6.00 ± 0.32^{***, ###}	5.00 ± 0.32^#	3.33 ± 0.18^#	5.00 ± 0.32^{***, ###}	9.50 ± 0.50^##	3.67 ± 0.36^{***, ###}	7.20 ± 0.37^##
LTZ + AE 110	8.00 ± 0.32^{***, ###}	8.80 ± 1.07^{***, ###}	4.00 ± 0.32^{*, ###}	5.25 ± 0.19^{***, ###}	6.20 ± 0.58^***	4.00 ± 0.32^{***, ###}	6.60 ± 0.81^###
LTZ + AE 200	9.00 ± 0.55^{***, ###}	9.20 ± 1.59^{***, ###}	3.40 ± 0.51^##	6.00 ± 0.32^{***, ###}	7.33 ± 0.36^**	4.00 ± 0.32^{***, ###}	7.60 ± 0.25^##

NC normal control; LTZ letrozole; CC clomiphene citrate; MET metformine; AE leaf aqueous extract of M. arboreus. Results are presented as mean S.E.M., n = 5. ^* p < 0.05, ^** p < 0.01 and ^*** p < 0.001 vs NC. ^# p < 0.05, ^## p < 0.01 and ^### p < 0.001 vs LTZ