Table 1.
Baseline characteristics of ACS patients and controls
| UAP (n = 537) | MI (n = 100) | Control (n = 129) | F or χ2 | p | |
|---|---|---|---|---|---|
| Age (years) | 64.96 ± 10.13 | 63.44 ± 10.51 | 57.43 ± 9.67* | 28.960 | 0.000 |
| Male (n, %) | 299 (56) | 78 (78) | 51 (40) | 33.833 | 0.000 |
| Smoker (n, %) | 89 (17) | 21 (21) | 13 (10)* | 11.350 | 0.003 |
| Hypertension (n, %) | 300 (56) | 67 (67) | 63 (49)* | 7.60 | 0.022 |
| DM (n, %) | 144 (27) | 24 (24) | 12 (9)* | 17.763 | 0.000 |
| AF (n, %) | 21 (4) | 5 (5) | 6 (5) | 0.337 | 0.845 |
| Previous stroke (n, %) | 49 (9) | 6 (6) | 9 (7) | 1.460 | 0.482 |
| FBG (mmol/L) | 5.11 (4.54, 6.48) | 5.96 (4.90, 8.23)** | 4.95 (4.51, 5.75) | 18.746 | < 0.001 |
| TC (mmol/L) | 3.72 (3.03, 4.64) | 3.50 (2.79, 5.01) | 3.83 (3.08, 4.53) | 0.363 | 0.834 |
| TG (mmol/L) | 1.34 (0.96, 1.94) | 1.54 (1.02, 2.01)** | 1.23 (0.86, 1.86) | 6.807 | 0.003 |
| HDL-C (mmol/L) | 0.90 (0.75, 1.06) | 0.83 (0.67, 1.00) | 0.95 (0.79, 1.14)* | 13.958 | 0.001 |
| LDL-C (mmol/L) | 2.01 (1.54, 2.62) | 1.98 (1.39, 2.86) | 2.08 (1.57, 2.56) | 0.173 | 0.917 |
| CRP (mg/L) | 1.20 (0.50, 3.60) | 2.30 (0.05, 6.18) | 1.20 (0.60, 3.30) | 1.158 | 0.560 |
| UA (μmol/L) | 301 (251, 364) | 317 (258, 398)** | 282 (243, 353) | 8.223 | 0.016 |
| SCr (μmol/L) | 67 (60.5, 72) | 70 (63.25, 86) | 63 (56.5, 69) | 34.574 | < 0.001 |
| D-dimer (mg/L) | 0.27 (0.19, 0.45) | 0.29 (0.19, 0.45) | 0.23 (0.11, 0.39) | 8.729 | 0.013 |
| Lp(a) (mg/L) | 225 (93.75, 387.75) | 237 (90, 470) | 217 (110, 453) | 0.143 | 0.931 |
| Neu5Ac (ng/ml) | 227 (114, 312) | 297 (220, 374) ** | 207 (114, 276) | 17.505 | < 0.001 |
| Coronary lesions (n, %) | |||||
| Three vessels | 205 (30) | 56 (37)** | – | 11.075 | 0.001 |
| Two vessels | 194 (26) | 27 (23) | – | 3.099 | 0.078 |
| Single vessel | 138 (44) | 17 (40) | – | 3.464 | 0.063 |
| Gensini score | 30.70 ± 28.61 | 53.04 ± 35.96** | – | 6.876 | 0.000 |
| CK-MB (U/L) | 12.20 (0.00, 17.00) | 40.62 (8.00, 42.00) ** | 9.49 (0.00, 14.00) | 35.032 | < 0.001 |
| TnI (μg/L) | 0.37 (0.00, 0.19) | 4.28 (0.07, 3.76) ** | 0.36 (0.00, 0.35) | 34.817 | < 0.001 |
*, p < 0.05 compared to MI patients;
*, p < 0.05 compared to UAP patients;
UAP Unstable angina pectoris, MI Myocardial infarction, DM Diabetes mellitus, AF Atrial fibrillation, FBG Fasting blood glucose, TC Total cholesterol, TG Triglyceride, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, CRP C-reactive protein, UA Uric acid, SCr Serum creatinine, Lp(a) Lipoprotein (a), Neu5Ac N-acetylneuraminic acid, CK-MB MB isoform of creatine kinase, TnI Troponin I