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Pharmacokinetic properties of ent-4g in ratsa.
| i.v. (rat, 7.5 mg/kg) |
p.o. (rat, 15 mg/kg) |
||||||
|---|---|---|---|---|---|---|---|
| CL (L·kg/h) |
t1/2 (h) |
AUC0–t (μg/h·L) |
Vss (L/kg) |
Tmax (h) |
Cmax (μg/L) |
AUC0–t (μg/h·L) |
F |
| 1.21 | 1.85 | 21,092.4 | 7.36 | 4.03 | 5897.5 | 12,463.8 | 29.5% |
Male SD rats (6–8 weeks old, 3 animals per group) were used for pharmacokinetics study.
