Table 3.
Effects of PUM on liver and body weight of rat
| Treatment groups | Initial body weight (g) | Final body weight (g)) | % increase in body weight | Absolute liver weight (g) | Relative liver weight (mg/g of body weight) |
|---|---|---|---|---|---|
| Control | 122.70 ± 2.05 | 219.33 ± 3.39 | 79.08 ± 0.52c | 8.16 ± 0.23cd | 37.18 ± 0.78cd |
| CCl4 (1 ml/kg bw) | 126.33 ± 2.62 | 177 ± 3.56 | 40.10 ± 0.79f | 9.12 ± 0.08a | 51.56 ± 1.02a |
| CCl4 + Silymarin (200 mg/kg bw) | 119.30 ± 0.94 | 187.67 ± 2.05 | 57.25 ± 0.76e | 8.37 ± 0.09bc | 44.59 ± 0.97b |
| CCl4 + PUM (150 mg/kg bw) | 121.70 ± 2.36 | 193 ± 3.55 | 58.63 ± 0.38e | 8.70 ± 0.08ab | 45.09 ± 0.97b |
| CCl4 + PUM (300 mg/kg bw) | 123.25 ± 2.05 | 215.25 ± 3.26 | 74.64 ± 0.25d | 8.40 ± 0.12bc | 39.02 ± 0.57c |
| PUM (150 mg/kg bw) | 122.50 ± 2.50 | 224 ± 4 | 82.86 ± 0.46b | 8.38 ± 0.14bc | 37.39 ± 0.65c |
| PUM (300 mg/kg bw) | 120 ± 0 | 226.50 ± 1.11 | 88.75 ± 0.93a | 7.90 ± 0.18d | 34.87 ± 0.82d |
Mean ± SD (n = 6 male rats); Means not sharing common superscript (a-f) indicate significance difference at P > 0.05. PUM Methanol extract of Pilea umbrosa