Table 2. . Study summary.
| Study (year, location) | Patient number | Study duration | Median age/female | Operative details | ICU care/mortality | General findings |
|---|---|---|---|---|---|---|
|
Aminian et al. (2020) (Tehran, Iran) SC, R |
Four diagnosed but one excluded Study number = 3 (one hospital) |
02/2020 | 75 (54–81)/n = 2 (66.6%) | Cholecystectomy: n = 1 (25%) Hernia repair: n = 1 (25%) Gastric bypass: n = 1 (25%) Hysterectomy: n = 1 (25%) |
NS; n = 1 (NS/33.3%) |
COVID-19 can complicate the perioperative course with diagnostic challenge and high potential fatality rate In locations with widespread infections and limited resources, risk of elective surgical procedures for index patient and community may outweigh the benefit In some situations, postponing elective surgical procedures might be right decision Another option would be routine or selective screening of patients for COVID-19 before elective surgical procedures |
|
Cai et al. (2020) (Wuhan, China) SC, R |
Study number = 7 (one hospital) |
01/01/2020 – 22/01/2020 |
60 (57–68)/n = 5 (71.4%) | Surgical time (median, range): 165 min (110–280) Blood loss (median range): 100 ml (50–200) VATS lobectomy: n = 4 (57.1%) VATS segmentectomy plus wedge resection: n = 1 (14.2%) Thoracotomy sleeve lobectomy: n = 1 (14.2%) Lobectomy plus bronchus reconstruction: n = 1 (14.2%) |
n = 3; n = 3 (42.9%/42.9%) |
Outbreak imposes major challenge in deciding and managing surgical operation on patients with lung cancer and other lung disorders Preliminary results from limited cases indicate that lung resection surgery might be a risk factor for death in patients with COVID-19 in the perioperative period |
|
Lei et al. (2020) (Wuhan, China) MC, R |
37 diagnosed but three excluded Study number = 34 (four hospitals) |
01/01/2020 – 05/02/2020 |
55 (21–84)/n = 20 (58.8%) | Surgical time (median; IQR): 178 (70–249) min ICU vs non-ICU: 200 vs 70 Breast: n = 2 (5.9%) Caesarean: n = 5 (14.7%) GI: n = 12 (35.3%) Gyne: n = 1 (2.9%) Neuro: n = 3 (8.8%) Ophthalmic: n = 1 (2.9%) Ortho: n = 6 (17.6%) Pulmonary: n = 3 (8.8%) Renal transplant: n = 1 (2.9%) Endoscopic: n = 10 (29.4%) Moderate-/high-risk: n = 22 (64.7%) (ICU vs non-ICU: 93.4 vs 42.1%) |
n = 15; n = 7 (44.1%/20.5%) |
Compared with non-ICU patients: ICU patients older, more likely to have underlying co-morbidities, underwent more complex surgeries and had more severe lab abnormalities (hyperleukocythemia, lymphopenia) |
|
Li et al. (2020) (Wuhan, China) SC, R |
Study number = 13 (one hospital) |
01/01/2020 – 20/02/2020 |
60.2 ± 5.6/n = 3 (23.1%) | Thoracic operations Lung: n = 11 Oesophagus: n = 2 |
n = 7; n = 5 (46.2%; 38.5%) |
COPD significantly associated with severity and death Chest operation was significantly associated with death COVID-19 is associated with poor prognosis for patients undergoing thoracic operation, especially for those with COPD Implementation of comprehensive protective measures is important to control nosocomial infection |
|
Panciani et al. (2020) (Brescia, Italy) SC, R |
Study number = 5 (one hospital) |
21/02/2020 – 23/03/2020 |
82 (77–86)/n = 0 (0%) | Neurosurgery: n = 3 (Craniotomy: n = 2) (Burr hole: n = 1) Endovascular treatment: n = 2 All for chronic subdural hematoma |
NS; n = 4 (NS; 80%) |
The authors observed mortality rate of 80% about 21.6-times greater than control data |
|
Yang et al. (2020) (Wuhan, China) SC, R |
Study number = 3 (one hospital) |
01/01/2020 – 20/02/2020 |
50.1 (mean)/n = 3 (100%) | Hysterectomy: n = 1 Radical hysterectomy: n = 1 Cytoreductive surgery: n = 1 |
n = 0; n = 0 | Severe infection may be related to older age, co-morbidities, malignant tumor and surgery in gynecologic hospitalizations Given the long and uncertain incubation period of COVID-19, screening for the virus infection should be carried out for all patients, both preoperatively and postoperatively Postponement of scheduled gynecologic surgery for patients in the epidemic area should be considered |
COPD: Chronic obstructive pulmonary disease; COVID-19: Coronavirus Disease 2019; ICU: Intensive care unit; IQR: Interquartile range; GI: Gastrointestinal; MC: Multicenter; NS: Nonsignificant; R: Retrospective; SC: Single center; VATS: Video assisted thoracic surgery.