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. 2020 Sep 14;11:394. doi: 10.1186/s13287-020-01825-1

Table 3.

SVF cells for diabetic foot and its pros and cons

SVF cells for diabetic foot Pros and cons Citations
Separation methods Enzymatic digestion Simple and convenient; possible immune response [52]
[53]
Physical method Safety; long digestion time; low cell yield
Cell populations Multi-cellular components Wide source; without culture; safety; effective [57]
Mechanism Differentiation Direct action; directly involved in vascular reconstruction [61]
Paracrine action Secrete various cytokines; promote vascular remodeling [66, 69, 71]
Cytokine action Cytokine interaction; promote cell proliferation and migration [77]