Table 2.
Upregulated Tumor Suppressor Genes in DFMO-Treated Jurkat Cells as Compared With Untreated Cells.
| Gene | Gene symbol | LogFc* | P value | |
|---|---|---|---|---|
| Tumor suppressor genes | CDKN2A Interacting Protein N-Terminal Like | DDIT3 | 3.26 | 7.57E-11 |
| PPARG Coactivator 1 Alpha | PPARGC1A | 2.64 | 0.000108 | |
| DLC1 Rho GTPase Activating Protein | DLC1 | 1.07 | 0.0345 | |
| Spalt Like Transcription Factor 4 | SALL4 | 4.44 | 0.607086 | |
| Suppression Of Tumorigenicity 7 | ST7 | 0.62 | 0.165587 | |
| Lysine Demethylase 3A | KDM3A | 0.77 | 0.0732 | |
| Lysine Demethylase 6A | KDM6A | 0.533 | 0.2491 | |
| Lysine Demethylase 7A | KDM7A | 0.90 | 0.0498 | |
| Tet Methylcytosine Dioxygenase 2 | TET2 | 0.34 | 0.4935 | |
| Cytochrome P450 Family 1 Subfamily B Member 1 | CYP1B1 | 0.79 | 0.5608 |
*fold change treated vs untreated.