Relative expression of miR-497 and Ihh detected by RT-qPCR in endochondral ossification models induced by bone morphogenetic gelatin. (A-C) Representative histological images of toluidine blue staining at 1, 2, and 3 weeks, respectively. The scale bar is 200 µm. (D) The downregulated expression of miR-497 at 1, 2, and 3 weeks. (E) The reversed expression of Ihh at 1, 2, and 3 weeks (For interpretation of the references to colours in this figure legend, refer to the online version of this article). *P < 0.05, ***P < 0.001.