Table 1.
Clinical information from 25 systemically ill cats used to study urinary F2-isoprostanes.
| Cat | Temp (37.2–39.4°C) |
Hct (0.37–0.55 L/L) |
SegNeut (3.0–12.0 × 109/L) |
BandNeut (0.0 × 109/L) |
Urea (2.5–11.4 mmol/L) |
Creatinine (44–142 µmol/L) |
ALT (3–69 U/L) |
ALP (20–157 U/L) |
Illness score | Diagnosis |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 39.8 | 0.32 | 16.8 | 0 | 3.2 | 88 | 43 | < 20 | 2 | Pancreatitis |
| 2 | 38.3 | 0.37 | 12.6 | 0 | 4.6 | 97 | 1,220 | 101 | 2 | LP hepatitis |
| 3 | 38.6 | 0.32 | 11.7 | 0 | 6.8 | 106 | 38 | 45 | 0 | IBD |
| 4 | 39.2 | 0.31 | 12.5 | 0 | 10 | 88 | 311 | 97 | 2 | Hyperthyroidism |
| 5 | 38.8 | 0.33 | 5.4 | 0 | 10.7 | 142 | 73 | 31 | 1 | CKD Stage 2 |
| 6 | 37.7 | 0.39 | 18.6 | 0.2 | 8.6 | 124 | 40 | 26 | 2 | LP rhinitis |
| 7 | 40.4 | 0.37 | 19.4 | 0.6 | 6.8 | 88 | 38 | < 20 | 3 | Pyothorax |
| 8 | 38.0 | 0.36 | 4.7 | 0 | 7.1 | 62 | 93 | 42 | 0 | Hyperthyroidism |
| 9 | 38.9 | 0.27 | 2.8 | 0 | 5 | 115 | 62 | 57 | 1 | Bacterial pneumonia |
| 10 | 38.5 | 0.35 | 6.1 | 0 | 15.3 | 186 | 76 | 89 | 2 | DKA |
| 11 | 39.3 | 0.39 | 8.4 | 0 | 17.5 | 124 | 119 | 100 | 1 | Urethral obstruction |
| 12 | 38.4 | 0.31 | 6.8 | 0 | 17.5 | 221 | 42 | 32 | 1 | CKD stage 2 |
| 13 | 37.8 | 0.39 | 7.4 | 0 | 16.8 | 159 | 127 | 98 | 1 | Hyperthyroidism |
| 14 | 37.6 | 0.48 | 11.1 | 0 | 10 | 106 | 47 | 67 | 0 | Chronic vomiting |
| 15 | 38.9 | 0.31 | 5.8 | 0 | 9.6 | 115 | 47 | 41 | 0 | Ascites |
| 16 | 38.3 | 0.48 | 12.4 | 0 | 16.1 | 124 | 138 | 54 | 2 | Renal lymphoma |
| 17 | 39.5 | 0.08 | 7.9 | 0.4 | 11.4 | 80 | 62 | < 20 | 3 | IMHA |
| 18 | 40.4 | 0.36 | 20.6 | 0.5 | 15.7 | 168 | 28 | 76 | 4 | Duodenal perforation |
| 19 | 37.7 | 0.43 | 11.8 | 0 | 7.5 | 115 | 46 | 80 | 0 | IBD |
| 20 | 37.8 | 0.28 | 17.3 | 0 | 5 | 44 | 24 | 25 | 1 | IBD |
| 21 | 38.8 | 0.37 | 12.1 | 0 | 3.9 | 53 | 210 | 121 | 2 | Hyperthyroidism |
| 22 | 38.9 | 0.32 | 12.5 | 0 | 13.2 | 203 | 88 | 97 | 2 | CKD stage 2 |
| 23 | 38.2 | 0.27 | 6.1 | 0 | 11.8 | 194 | 86 | 53 | 2 | Pancreatic carcinoma |
| 24 | 37.8 | 0.29 | 6.3 | 0 | 17.1 | 2 | 71 | 31 | 2 | CKD stage 2 |
| 25 | 37.7 | 0.35 | 6.1 | 0 | 15.4 | 2 | 76 | 40 | 1 | CKD stage 2 |
Numbers in parentheses are reference intervals. ALP = alkaline phosphatase; ALT = alanine aminotransferase; BandNeut = band neutrophils; CKD = chronic kidney disease; DKA = diabetic ketoacidosis; Hct = hematocrit; IBD = inflammatory bowel disease; IMHA = immune-mediated hemolytic anemia; LP = lymphoplasmacytic; RI = reference interval; SegNeut = segmented neutrophil. Values in bold met the criteria to contribute to the systemic illness score utilized in our study. One point each was attributed to: fever on presentation (≥ 39.4°C or 103.0°F), neutrophilia (> 12.0 × 109/L), presence of band neutrophils on blood smear analysis, biochemical evidence of organ involvement and/or dysfunction (creatinine > 142 µmol/L; ALT > 138 U/L; ALP > 157 U/L), and anemia (hematocrit < 0.30 L/L). Systemic illness scores were as follows: 0–1 = mild systemic illness, 2–3 = moderate systemic illness, 4–5 = severe systemic illness.