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. 2020 Jul 27;32(5):664–674. doi: 10.1177/1040638720943584

Figure 3.

Figure 3.

Association of gastrointestinal histologic lesions with serum soluble RAGE (sRAGE) concentrations in dogs with chronic inflammatory enteropathy (CIE; n = 102). A. Patients with moderate-to-severe histologic lesions (score 2–3) had numerically lower serum sRAGE concentrations (median: 257 ng/L, interquartile range [IQR]: 126–413 ng/L; n = 56) compared to dogs with no more than mild histologic lesions (score: 0–1; median: 326 ng/L, IQR: 207–573 ng/L; n = 46), but no significant difference in serum sRAGE concentration was found between the groups of dogs (p = 0.157). B. Cumulative histologic lesion scores in the duodenum in dogs with CIE and a serum sRAGE concentration ≤ 340 ng/L were significantly higher (median: 4, IQR: 2–6; n = 61) compared to dogs with a serum sRAGE concentration > 340 ng/L (median: 3, IQR: 1–5; n = 34; p = 0.013). Asterisk (*) indicates significant difference at p < 0.05.