Table 4.

Multivariable Cox regression analysis of predictors of LTFU among HIV-positive adult subjects on ART at Debre Markos Referral Hospital, North West Ethiopia, from January 30, 2008, to January 26, 2018

Variables	Last status		CHR (95% CI)	AHR (95% CI)	p value
	Event	Censored
Sex
Male	40	162	1.0	1.0
Female	44	238	0.81 (0.53,1.23)	0.88 (0.54, 1.42)	0.58
ART regimen
1a	8	56	1.0	1.0
1b	13	48	1.6 (0.7, 3.9)	1.6 (0.6, 3.9)	0.37
1c	14	66	1.99 (0.83, 4.8)	2.79 (1.07, 7.23)	0.32
1d	9	31	2.4 (0.94, 6.4)	3.14 (1.13, 8.08)	0.19
1e	40	199	6.7 (3.14, 14.7)	9.3 (3.75 , 23.8)	0.10
History of ART adherence
Poor	23	77	1.0	1.0
Good	61	323	0.5(0.3, 0.8)	1.2(0.3, 0.9)	0.20
WHO clinical stage
Stage I	11	106	1.0	1.0
Stage II	8	66	0.7 (0.29, 0.1.81)	1.09 (0.42, 2.85)	0.45
Stage III	48	172	1.44 (0.75, 2.78)	1.73 (0.87, 3.46)	0.20
Stage IV	17	56	1.8 (0.83, 3.8)	2.75 (1.23, 6.16)	0.01
Residence
Urban	55	217	1.0	1.0
Rural	29	183	0.5 (0.33, 0.8)	0.6 (0.37, 0.99)	0.046
Phone
Yes	68	352	1.0	1.0
No	16	48	1.5 (0.87, 2.6)	1.9 (1.14, 3.4)	0.04
Age categories
15–24	13	40	1.0	1.0
25–34	41	169	0.44 (.22, 0.88)	0.67 (0.35, 1.29)	0.20
35–44	22	127	0.4 (0.22, 0.86)	0.32 (0.15, 0.67)	0.20
≥ 45	8	64	0.4 (0.17, 0.99)	0.33 (0.13, 0.83)	0.19
Baseline CD4 Count
≤ 50	11	46	1.0	1.0
50–150	28	125	0.68 (0.34, 1.37)	0.76 (0.37, 1.57)	0.46
150–200	12	53	0.58 (0.26, 1.33)	0.52 (0.21, 1.28)	0.16
≥ 200	33	176	1.14 (0.57, 2.27)	0.68 (0.32, 1.43)	0.31
History of TB infection
No	56	273	1.0	1.0
Yes	25	126	0.58 (0.36, 0.94	0.74 (0.43, 1.26)	0.27
History of ART regimen change
No	54	273	1.0	1.0
Yes	30	127	0.72 (0.46, 1.14)	1.59 (0.9, 2.8)	0.11