Fig. 2.

PCA of imprinted DMR methylation. DNA methylation of the imprinted DMRs of the four probands, their mothers and siblings, and 12 age-matched healthy controls was compared by PCA. Symbol code: circles represent members of family 1, triangles members of family 2, rhombi members of family 3, and squares the controls. Color code: probands are represented in dark blue, mothers in pink, siblings in light blue, controls in gray