Table 1.
Associations between angiopoietin-like 4 (ANGPTL4) expression and clinicopathologic factors of 161 patients with TNBC
| Characteristics | ANGPTL4 expression (cases) | P value | |
|---|---|---|---|
| Weak | High | ||
| Total | 66 | 95 | |
| Age (years) | |||
| ≤ 40 | 9 (13.6%) | 20 (21.1%) | 0.228 |
| > 40 | 57 (86.4%) | 75 (78.9%) | |
| Family history of cancer | 0.600 | ||
| No | 52 (78.8%) | 78 (82.1%) | |
| Yes | 14 (21.2%) | 17 (17.9%) | |
| Menopause | 0.435 | ||
| No | 32 (51.5%) | 52 (45.3%) | |
| Yes | 34 (48.5%) | 43 (54.7%) | |
| History of other neoplasms | 0.601 | ||
| No | 63 (95.5%) | 92 (96.8%) | |
| Yes | 3 (4.5%) | 3 (3.2%) | |
| Stage | 0.265 | ||
| 0/ I/ II | 44 (66.7%) | 71 (74.7%) | |
| III | 22 (33.3%) | 24 (25.3%) | |
| T status | 0.395 | ||
| Tis/ T1/ T2 | 55 (83.3%) | 74 (77.9%) | |
| T3/ T4 | 11 (16.7%) | 21 (22.1%) | |
| Lymph node metastasis | 0.139 | ||
| N0 | 29 (43.9%) | 53 (55.8%) | |
| N1–3 | 37 (56.1%) | 42 (44.2%) | |
| Histological differentiation | 0.087 | ||
| 1/ 2 | 24 (50.0%) | 26 (38.6%) | |
| 3 | 21 (50.0%) | 44 (61.4%) | |
| Vascular invasion | |||
| No | 47 (71.2%) | 80 (84.2%) | 0.047 |
| Yes | 19 (28.8%) | 15 (15.8%) | |
| Disease recurrence | |||
| No | 39 (59.1%) | 75 (78.9%) | 0.006 |
| Yes | 27 (40.9%) | 20 (21.1%) | |
| Progression | 0.333 | ||
| Local recurrence | 16 (59.3%) | 9 (45.0%) | |
| Distant metastasis | 11 (40.7%) | 11 (55.0%) | |