Table 3.

Univariate and multivariate analyses of the overall survival of the 161 TNBC patients

Variable	Overall survival
	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Age ≤ 40 years old	1.133 (0.549–2.340)	0.736
Family history of cancer	1.572 (0.705–3.505)	0.269
Menstruating	1.131 (0.641–1.996)	0.670
History of other neoplasms	1.232 (0.299–5.086)	0.773
Stage III disease	4.420 (2.496–7.827)	0.000	2.493 (1.276–4.873)	0.008
T3/ T4	2.567 (1.391–4.735)	0.003	0.995 (0.436–2.271)	0.497
Lymph node metastasis	4.440 (2.262–8.713)	0.000	2.543 (1.151–5.620)	0.021
Poor tumor differentiation	1.547 (0.788–3.040)	0.205
Vascular invasion	3.567 (2.002–6.355)	0.000	1.725 (0.841–3.535)	0.102
Distant metastasis	1.775 (0.899–3.503)	0.098
Low ANGPTL4 expression	2.180 (1.232–3.860)	0.006	1.776 (0.998–3.161)	0.051

Stage III disease, lymph node metastasis and low ANGPTL4 expression are independent risk factors for shorter OS