Table 1.

Definition and basic information of the concepts and relations types as used in the n2c2 challenge

Type name			Records
Concept	Relation	Examples	Concepts	Relations
Drug		“The patient suffers from steroid-induced hyperglycemia.”	26 803
		“Patient prescribed 1 x 20 mg Prednisone tablet daily for 5 days.”
Strength	Strength-Drug	“Patient has been switched to lisinopril10mg 1 tablet PO QD.”	10 922	10 950
		“Patient prescribed 1-2 325 mg / 10 mgNorco pills every 4-6 hours as needed for pain.”
Dosage	Dosage-Drug	“Patient has been switched to lisinopril 10mg 1 tablet PO QD.”	6900	6939
		“Patient prescribed 1-2 325 mg / 10 mg Norco pills every 4-6 hours as needed for pain.”
Duration	Duration-Drug	“Patient prescribed 1 x 20 mg Prednisone tablet daily for 5 days.”	966	1069
Frequency	Frequency-Drug	“Patient prescribed 1 x 20 mg Prednisone tablet daily for 5 days.”	10 293	10 352
		“Patient has been switched to lisinopril 10mg 1 tablet PO QD.”
		“tylenolQ8H PRN”
Form	Form-Drug	“Patient prescribed 1 x 20 mg Prednisonetablet daily for 5 days.”	11 006	11 048
		“Patient prescribed 1-2 325 mg / 10 mg Norcopills every 4-6 hours as needed for pain.”
Route	Route-Drug	“Patient has been switched to lisinopril 10mg 1 tablet PO QD.”	8987	9086
		“Patient received 100 Units/kg IV heparin sodiuminjection for treatment of deep vein thrombosis.”
Reason	Reason-Drug	“Patient received 100 Units/kg IV heparin sodium injection for treatment of deep vein thrombosis.”	6384	8611
		“Patient prescribed 1-2 325 mg / 10 mg Norco pills every 4-6 hours as needed for pain.”
ADE	ADE-Drug	“The patient suffers from steroid-induced hyperglycemia.”	1579	1841
		“Patient is experiencing muscle pain, secondary to statin therapy for coronary artery disease.”

ADE: adverse drug event.