Table 1. Histological grading scale for defects in articular cartilage.
Category | Score (Points) | |
1. | Filling of defect relative to surface of | |
normal adjacent cartilage | 0 | |
>90% | 1 | |
75-90% | 2 | |
50-74% | 3 | |
25-49% | 4 | |
<25% | ||
2. | Cellular morphology (percentage of | |
chondrocytes) | 0 | |
>90% | 1 | |
75-90% | 2 | |
50-74% | 3 | |
25-49% | 4 | |
Mostly fibroblast-like cells | ||
3. | Surface architecture | |
Normal | 0 | |
Slightly irregular | 1 | |
Fibrillation | 2 | |
Distrupted | 3 | |
4. | Matrix staining with Safranin O | |
Normal | 0 | |
Slightly reduced | 1 | |
Moderately reduced | 2 | |
Substantially reduced | 3 | |
None | 4 | |
5. | Tidemark formation | |
>90% | 0 | |
75-90% | 1 | |
50-74% | 2 | |
25-49% | 3 | |
<25% | 4 | |
5. | Integration of repair tissue with adjacent | |
articular cartilage | 0 | |
Normal | 1 | |
Decreased cellularity | 2 | |
Small gap | 3 | |
Discontinuity | ||
7. | Percentage of new subchondral bone | |
>90% | 0 | |
75-90% | 1 | |
50-74% | 2 | |
25-49% | 3 | |
<25% | 4 |