Table 1. Differences of demographic and clinical characteristics between effective and ineffective groups.
Characteristics | Entire cohort | Training set | Validation set | External dataset | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Effective [N = 127] | Ineffective [N = 28] | Total [N = 155] | P-value | Effective (N = 90) | Ineffective (N = 21) | Total (N = 111) | P-value | Effective (N = 37) | Ineffective (N = 7) | Total (N = 44) | P-value | Effective (N = 17) | Ineffective (N = 4) | Total (N = 21) | |
Gender | P < 0.001 | P < 0.01 | P < 0.01 | ||||||||||||
Female | 38[30%] | 8[28.6%] | 46[29.7%] | 57[63.3%] | 16[76.2%] | 73[65.8%] | 32[86.5%] | 4[57.1%] | 36[81.8%] | 7(59%) | 1(25%) | 8(38%) | |||
Male | 89[70%] | 20[71.4%] | 109[70.3%] | 33[36.7%] | 5[23.8%] | 38[34.2%] | 5[13.5%] | 3[42.9%] | 8[18.2%] | 10(41%) | 3(75%) | 13(62%) | |||
Age | |||||||||||||||
Mean [SD] | 33.9[12.6] | 43.8[12.6] | 35.7[13.1] | 34.8[12.9] | 43.5[11.8] | 36.5[13.1] | 31.8[11.7] | 44.9[15.6] | 33.8[13.1] | 38.6(13.3) | 42.0(22.0) | 39.2(14.7) | |||
Median [MIN, MAX] | 31 [14,66] | 45[22,63] | 33[14,66] | 32.5[14,66] | 47[22,61] | 34[14,66] | 29[16,64] | 43[22,63] | 30.5[16,64] | 40 [16,57] | 31.5[30,75] | 39[16,75] | |||
BMI | P < 0.01 | P < 0.05 | P < 0.05 | ||||||||||||
Mean [SD] | 23.0[2.9] | 24.7[3.2] | 23.3[3.1] | 22.9[3.6] | 24.8[3.5] | 23.3[3.6] | 22.7[2.6] | 24.5[2.7] | 23[2.6] | 22.6(4.4) | 22.8(0.5) | 22.6(3.9) | |||
Median [MIN, MAX] | 22.9[16.2,30.9] | 24.3[18.5,31.5] | 23.0[16.2,31.5] | 23[10.9,29.3] | 24.3[18.5,31.5] | 23.4[10.9,31.5] | 22.6[17,30.9] | 24.2[21.5,29.8] | 22.7[17,30.9] | 21.9[17.6,30.9] | 23.0[22.0,23.0] | 22.0[17.6,30.9] | |||
Atrophic Rhinitis | |||||||||||||||
Yes | 1[0.8%] | 3[10.7%] | 4[2.6%] | 1[1.1%] | 2[9.5%] | 3[2.7%] | 0[0%] | 1[14.3%] | 1[2.3%] | 0(0%) | 0(0%) | 0(0%) | |||
No | 126[99.2%] | 25[89.3%] | 151[97.4%] | 89[98.9%] | 19[90.5%] | 108[97.3%] | 37[100%] | 6[85.7%] | 43[97.7%] | 17(100%) | 4(100%) | 21(100%) | |||
Nasal Polyps | |||||||||||||||
Yes | 10[7.9%] | 6[21.4%] | 16[10.3%] | 5[5.6%] | 6[28.6%] | 11[9.9%] | 5[13.5%] | 0[0%] | 5[11.4%] | 2(11.8%) | 0(0%) | 2(9.5%) | |||
No | 117[92.1%] | 22[78.6%] | 139[89.7%] | 85[94.4%] | 15[71.4%] | 100[90.1%] | 32[86.5%] | 7[100%] | 39[88.6%] | 15(88.2%) | 4(100%) | 19(90.5%) | |||
Epistaxis | |||||||||||||||
Yes | 19[15.0%] | 4[14.3%] | 23[14.8%] | 16[17.8%] | 4[19%] | 20[18%] | 3[8.1%] | 0[0%] | 3[6.8%] | 5(29.4%) | 0(0%) | 5(23.8%) | |||
No | 108[85.0%] | 24[85.7%] | 132[85.2%] | 74[82.2%] | 17[81%] | 91[82%] | 34[91.9%] | 7[100%] | 41[93.2%] | 12(70.6%) | 4(100%) | 16(76.2%) | |||
Nasosinusitis | P < 0.05 | ||||||||||||||
Yes | 23[18.1%] | 16[57.1%] | 39[25.2%] | 15[16.7%] | 12[57.1%] | 27[24.3%] | 3(17.6%) | 3(75%) | 6(28.6%) | 3(17.6%) | 3(75%) | 6(28.6%) | |||
No | 104[81.9%] | 12[42.9%] | 116[74.8%] | 75[83.3%] | 9[42.9%] | 84[75.7%] | 14(82.4%) | 1(25%) | 15(71.4%) | 14(82.4%) | 1(25%) | 15(71.4%) | |||
High Blood Pressure | |||||||||||||||
Yes | 18[14.2%] | 7[25.0%] | 25[16.1%] | 11[12.2%] | 5[23.8%] | 16[14.4%] | 7[18.9%] | 2[28.6%] | 9[20.5%] | 4(24%) | 1(25.0%) | 5(24%) | |||
No | 109[85.8%] | 21[75.0%] | 130[83.9%] | 79[87.8%] | 16[76.2%] | 95[85.6%] | 30[81.1%] | 5[71.4%] | 35[79.5%] | 13(76%) | 3(75.0%) | 16(76%) | |||
Diabetes | |||||||||||||||
Yes | 7[5.5%] | 3[10.7%] | 10[6.5%] | 6[6.7%] | 2[9.5%] | 8[7.2%] | 1[2.7%] | 1[14.3%] | 2[4.5%] | 3(17.6%) | 0(0%) | 3(14.3%) | |||
No | 120[94.5%] | 25[89.3%] | 145[93.5%] | 84[93.3%] | 19[90.5%] | 103[92.8%] | 36[97.3%] | 6[85.7%] | 42[95.5%] | 14(82.4%) | 4(100%) | 18(85.7%) | |||
Seansonal Allergy History | |||||||||||||||
Yes | 46[36.2%] | 2[7.1%] | 48[31.0%] | 34[37.8%] | 1[4.8%] | 35[31.5%] | 12[32.4%] | 1[14.3%] | 13[29.5%] | 7(41.2%) | 0(0%) | 7(33.3%) | |||
No | 81[63.8%] | 26[92.9%] | 107[69.0%] | 56[62.2%] | 20[95.2%] | 76[68.5%] | 25[67.6%] | 6[85.7%] | 31[70.5%] | 10(58.8%) | 4(100%) | 14(66.7%) | |||
Intranasal Corticosteroids History | |||||||||||||||
Yes | 40[31.5%] | 7[25.0%] | 47[30.3%] | 29[32.2%] | 5[23.8%] | 34[30.6%] | 11[29.7%] | 2[28.6%] | 13[29.5%] | 7(41.2%) | 1(25%) | 8(38.1%) | |||
No | 87[68.5%] | 21[75.0%] | 108[69.7%] | 61[67.8%] | 16[76.2%] | 77[69.4%] | 26[70.3%] | 5[71.4%] | 31[70.5%] | 10(58.8%) | 3(75%) | 13(61.9%) | |||
History Of Nasal Bone Fracture | |||||||||||||||
Yes | 10[7.9%] | 5[17.9%] | 15[9.7%] | 5[5.6%] | 5[23.8%] | 10[9%] | 5[13.5%] | 0[0%] | 5[11.4%] | 2(11.8%) | 0(0%) | 2(9.5%) | |||
No | 117[92.1%] | 23[82.1%] | 140[90.3%] | 85[94.4%] | 16[76.2%] | 101[91%] | 32[86.5%] | 7[100%] | 39[88.6] | 15(88.2%) | 4(100%) | 19(90.5%) | |||
Nasal Surgery History | P < 0.05 | ||||||||||||||
Yes | 13[10.2%] | 12[42.9%] | 25[16.1%] | 10[11.1%] | 10[47.6%] | 20[18%] | 8[21.6%] | 4[57.1%] | 12[27.3%] | 3(17.6%) | 1(25%) | 4(19.0%) | |||
No | 114[89.8%] | 16[57.1%] | 130[83.9%] | 80[88.9%] | 11[52.4%] | 91[82%] | 29[78.4%] | 3[42.9%] | 32[72.7%] | 14(82.4%) | 3(75%) | 17(81.0%) | |||
Family History | |||||||||||||||
Yes | 33[26.0%] | 6[21.4%] | 39[25.2%] | 21[23.3%] | 4[19%] | 25[22.5%] | 12[32.4%] | 2[28.6%] | 14[31.8%] | 5(29.4%) | 1(25%) | 6(28.6%) | |||
No | 94[74.0%] | 22[78.6%] | 116[74.8%] | 69[76.7%] | 17[81%] | 86[77.5%] | 25[67.6%] | 5[71.4%] | 30[68.2%] | 12(70.6%) | 3(75%) | 15(71.4%) | |||
Smoking | |||||||||||||||
Yes | 31[24.4%] | 10[35.7%] | 41[26.5%] | 21[23.3%] | 8[38.1%] | 29[26.1%] | 10[27%] | 2[28.6%] | 12[27.3%] | 9(52.9) | 2(50.0%) | 11(52.4%) | |||
No | 96[75.6%] | 18[64.3%] | 114[73.5%] | 69[76.7%] | 13[61.9%] | 82[73.9%] | 27[73%] | 5[71.4%] | 32[72.7%] | 8(47.1%) | 2(50.0%) | 10(47.6%) | |||
Follow-Up Time[Year] | |||||||||||||||
Mean [SD] | 1.9[1.4] | 2.3[1.3] | 2.0[1.4] | 2[1.3] | 2.4[1.3] | 2[1.4] | 1.9[1.4] | 2.1[1.2] | 1.9[1.3] | 0.38(0.21) | 0.3(0.24) | 0.37(0.21) | |||
Median [MIN, MAX] | 1.72[0.03,4.62] | 1.7[0.28,4.43] | 1.7[0.03,4.63] | 1.8[0,4.3] | 2.8[0.5,4.4] | 1.7[0.03,4.6] | 1.6[0.1,4.4] | 2.2[0.3,3.4] | 1.8[0.1,4.4] | 0.43[0.05,0.66] | 0.32[0.06,0.52] | 0.43[0.05,0.66] | |||
Length Of Hospital Stay[Day] | |||||||||||||||
Mean [SD] | 4.8[1.0] | 4.64[0.87] | 4.7[1.0] | 4.8[1.1] | 4.8[0.9] | 4.8[1] | 4.6[1.2] | 4.1[0.7] | 4.5[1.1] | 4.5(0.5) | 4.8(0.5) | 4.5(0.5) | |||
Median [MIN, MAX] | 5[3,10] | 5[3,7] | 5[3,10] | 5[3,10] | 5[4,7] | 5[3,10] | 4[0,7] | 4[3,5] | 4[0,7] | 4[4,5] | 5[4,5] | 5[4,5] | |||
Proposed classification system of SD | |||||||||||||||
Type I | 20[15.7%] | 1[3.6%] | 21[13.5%] | 12[13.3%] | 1[4.8%] | 13[11.7%] | 8[21.6%] | 0[0%] | 8[18.2%] | 2[11.8%] | 0[0%] | 2[9.5%] | |||
Type II | 83[65.4%] | 22[78.6%] | 105[67.7%] | 58[64.4%] | 16[76.2%] | 74[66.7%] | 25[67.6%] | 6[85.7%] | 31[70.5%] | 1[5.9%] | 2[50%] | 3[14.3%] | |||
Type III | 20[15.7%] | 4[14.3%] | 24[15.5%] | 18[20%] | 3[14.3%] | 21[18.9%] | 2[5.4%] | 1[14.3%] | 3[6.8%] | 9[52.9%] | 1[25%] | 10[47.6%] | |||
Type IV | 4[3.1%] | 1[3.6%] | 5[3.2%] | 2[2.2%] | 1[4.8%] | 3[2.7%] | 2[5.4%] | 0(0%) | 2[4.5%] | 5[29.4%] | 1[25%] | 6[28.6%] | |||
Additional Surgery | |||||||||||||||
Middle Turbinoplasty | |||||||||||||||
Yes | 11[8.7%] | 2[7.1%] | 13[8.4%] | 9[10%] | 1[4.8%] | 10[9%] | 2[5.4%] | 1[14.3%] | 3[6.8%] | 2(11.8%) | 0(0%) | 2(9.5%) | |||
No | 116[91.3%] | 26[92.9%] | 142[91.6%] | 81[90%] | 20[95.2%] | 101[91%] | 35[94.6%] | 6[85.7%] | 41[93.2%] | 15(88.2%) | 4(100%) | 19(90.5%) | |||
Inferior Turbinoplasty | |||||||||||||||
Yes | 58[45.7%] | 10[35.7%] | 68[43.9%] | 40[44.4%] | 8[38.1%] | 48[43.2%] | 18[48.6%] | 2[28.6%] | 20[45.5%] | 7(41.2%) | 4(100%) | 11(52.4%) | |||
No | 69[54.3%] | 18[64.3%] | 87[56.1%] | 50[55.6%] | 13[61.9%] | 63[56.8%] | 19[51.4%] | 5[71.4%] | 24[54.5%] | 10(58.8%) | 0(0%) | 10(47.6%) | |||
Augmentation Rhinoplasty | |||||||||||||||
Yes | 8[6.2%] | 0[0%] | 8[5.2%] | 6[6.7%] | 0[0%] | 6[5.4%] | 2[5.4%] | 0[0%] | 2[4.5%] | 3(17.6%) | 0(0%) | 3(14.3%) | |||
No | 119[85.8%] | 28[100%] | 147[94.8%] | 84[93.3%] | 21[100%] | 105[94.6%] | 35[94.6%] | 7[100%] | 42[95.5%] | 14(82.4%) | 4(100%) | 18(85.7%) | |||
RFVR Of The Inferior Turbinate | |||||||||||||||
Yes | 8[6.2%] | 1[3.6%] | 9[5.8%] | 5[5.6%] | 0[0%] | 5[4.5%] | 3[8.1%] | 1[14.3%] | 4[9.1%] | 1(5.9%) | 1(25%) | 2(9.5%) | |||
No | 109[85.8%] | 27[96.4%] | 146[94.2%] | 85[94.4%] | 21[100%] | 106[95.5%] | 34[91.9%] | 6[85.7%] | 40[90.9%] | 16(94.1%) | 3(75%) | 19(90.5%) | |||
Nasal Bone Fracture Reduction | |||||||||||||||
Yes | 4[3.1%] | 1[3.6%] | 5[3.2%] | 2[2.2%] | 1[4.8%] | 3[2.7%] | 2[5.4%] | 0[0%] | 2[4.5%] | 3(17.6%) | 0(0%) | 3(14.3%) | |||
No | 123[96.9%] | 27[96.4%] | 150[96.8%] | 88[97.8%] | 20[95.2%] | 108[97.3%] | 35[94.6%] | 7[100%] | 42[95.5%] | 14(82.4%) | 4(100%) | 18(85.7%) | |||
Endoscopic Sinus Surgery | |||||||||||||||
Yes | 7[5.5%] | 7[25.0%] | 14[9.0%] | 4[4.4%] | 5[23.8%] | 9[8.1%] | 3[8.1%] | 2[28.6%] | 5[11.4%] | 0(0%) | 2(50.0%) | 2(9.5%) | |||
No | 120[94.5%] | 21[75.0%] | 141[91.0%] | 86[95.6%] | 16[76.2%] | 102[91.9%] | 34[91.9%] | 5[71.4%] | 39[88.6%] | 17(100%) | 2(50.0%) | 19(90.5%) | |||
SNOT-22 | |||||||||||||||
Need To Blow Nose | P < 0.001 | P < 0.001 | P < 0.001 | ||||||||||||
Mean [SD] | 3.6[1.0] | 2.9[1.3] | 3.5[1.1] | 3.7[1] | 2.8[1.3] | 3.5[1.1] | 3.5[1] | 3.3[1.4] | 3.5[1] | 3.2[1] | 3.5[1] | 3.3[1] | |||
Median [MIN, MAX] | 4.0 [0.0,5.0] | 4.0 [0.0,5.0] | 4.0 [0.0,5.0] | 4[1,5] | 3[0,4] | 4[0,5] | 4[1,5] | 4[1,5] | 4[1,5] | 3[2,5] | 4[2,4] | 3[2,5] | |||
Runny Nose | P < 0.001 | P < 0.001 | P < 0.01 | ||||||||||||
Mean [SD] | 3.2[1.4] | 2.4[1.8] | 3.1[1.5] | 3.3[1.4] | 2.3[1.8] | 3.1[1.5] | 3.1[1.5] | 2.9[1.5] | 3.1[1.5] | 2.9[1.2] | 2.8[0.5] | 2.9[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 4.0 [0.0,5.0] | 3.0 [0.0,5.0] | 4[0,5] | 2[0,5] | 3[0,5] | 3[0,5] | 2[2,5] | 3[0,5] | 3[1,5] | 3[2,3] | 3[1,5] | |||
Post Nasal Discharge | P < 0.001 | P < 0.001 | P < 0.01 | ||||||||||||
Mean [SD] | 2.9[1.0] | 2.4[1.4] | 2.8[1.1] | 2.9[1] | 2.2[1.4] | 2.8[1.1] | 2.8[1] | 2.9[1.5] | 2.8[1.1] | 3[0.9] | 4.3[1.5] | 3.2[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 2[0,5] | 3[0,5] | 3[1,4] | 2[1,5] | 3[1,5] | 3[2,4] | 5[2,5] | 3[2,5] | |||
Thick Nasal Discharge | |||||||||||||||
Mean [SD] | 2.3[1.2] | 2.2[1.4] | 2.3[1.3] | 2.4[1.2] | 2.1[1.4] | 2.3[1.3] | 2.2[1.2] | 2.6[1.5] | 2.3[1.2] | 2.4[0.6] | 3.8[0.5] | 2.6[0.8] | |||
Median [MIN, MAX] | 2.0 [0.0,5.0] | 2.0 [0.0,5.0] | 2.0 [0.0,5.0] | 2[0,5] | 2[0,5] | 2[0,5] | 2[0,5] | 2[1,5] | 2[0,5] | 2[2,4] | 4[3,4] | 2[2,4] | |||
Sneezing | P < 0.001 | P < 0.001 | P < 0.001 | ||||||||||||
Mean [SD] | 3.5[1.5] | 2.1[1.5] | 3.2[1.6] | 3.5[1.5] | 2[1.6] | 3.2[1.6] | 3.5[1.6] | 2.4[1.3] | 3.3[1.6] | 3.2[1.5] | 2.5[0.6] | 3[1.4] | |||
Median [MIN, MAX] | 4.0 [0.0,5.0] | 4.0 [0.0,5.0] | 4.0 [0.0,5.0] | 4[0,5] | 2[0,5] | 4[0,5] | 4[1,5] | 2[1,5] | 3.5[1,5] | 3[0,5] | 2.5[2,3] | 3[0,5] | |||
Cough | P < 0.001 | P < 0.001 | P < 0.001 | ||||||||||||
Mean [SD] | 2.5[0.9] | 1.7[1.0] | 2.3[1.0] | 2.5[0.9] | 1.6[1] | 2.3[1] | 2.5[0.9] | 2[1] | 2.4[0.9] | 2.8[0.9] | 2.3[1] | 2.7[0.9] | |||
Median [MIN, MAX] | 3.0 [0.0,4.0] | 3.0 [0.0,4.0] | 2.0 [0.0,4.0] | 3[0,4] | 2[0,4] | 2[0,4] | 2[1,4] | 2[0,3] | 2[0,4] | 3[2,5] | 2.5[1,3] | 3[1,5] | |||
Sense Of Taste Or Smell | |||||||||||||||
Mean [SD] | 2.9[1.4] | 2.5[1.3] | 2.9[1.4] | 3[1.4] | 2.6[1.3] | 2.9[1.4] | 2.8[1.3] | 2.4[1.5] | 2.7[1.3] | 2.8[1] | 2.8[0.5] | 2.8[0.9] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 2[0,5] | 3[0,5] | 3[1,5] | 3[2,3] | 3[1,5] | |||
Blockage/Congestion Of Nose | P < 0.001 | P < 0.05 | P < 0.05 | ||||||||||||
Mean [SD] | 4.6[1.0] | 3.9[1.6] | 4.4[1.2] | 4.6[0.9] | 4.1[1.4] | 4.5[1.1] | 4.5[1.1] | 3.1[1.9] | 4.3[1.3] | 4.2[1.1] | 4.8[0.5] | 4.3[1.1] | |||
Median [MIN, MAX] | 5.0 [0.0,5.0] | 5.0 [0.0,5.0] | 5.0 [0.0,5.0] | 5[1,5] | 5[0,5] | 5[0,5] | 5[1,5] | 4[0,5] | 5[0,5] | 5[1,5] | 5[4,5] | 5[1,5] | |||
Ear Fullness | |||||||||||||||
Mean [SD] | 3.2[1.2] | 2.6[1.3] | 3.1[1.2] | 3.3[1.2] | 2.8[1.3] | 3.2[1.2] | 3.2[1.2] | 2.1[1.2] | 3[1.2] | 3[0.9] | 3.5[1] | 3.1[0.9] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,4.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,4] | 3[0,5] | 3[0,5] | 2[0,4] | 3[0,5] | 3[1,4] | 4[2,4] | 3[1,4] | |||
Ear Pain | P < 0.001 | P < 0.001 | P < 0.001 | ||||||||||||
Mean [SD] | 2.5[1.3] | 1.6[1.3] | 2.3[1.3] | 2.5[1.2] | 1.4[1.2] | 2.3[1.3] | 2.5[1.4] | 2.3[1.3] | 2.5[1.4] | 2.2[1.3] | 3.8[0.5] | 2.5[1.3] | |||
Median [MIN, MAX] | 2.0 [0.0,5.0] | 2.0 [0.0,4.0] | 2.0 [0.0,5.0] | 2[0,5] | 1[0,4] | 2[0,5] | 2[0,5] | 2[0,4] | 2[0,5] | 2[0,4] | 4[3,4] | 3[0,4] | |||
Dizziness | P < 0.001 | P < 0.01 | P < 0.01 | ||||||||||||
Mean [SD] | 3.1[1.1] | 2.5[1.5] | 3.0[1.2] | 3.2[0.9] | 2.4[1.5] | 3[1.1] | 3.2[1.2] | 2.9[1.5] | 3.1[1.2] | 2.6[1.1] | 4[0] | 2.9[1.2] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,4.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,4] | 3[0,5] | 3[0,5] | 3[0,4] | 3[0,5] | 3[0,4] | 4[4,4] | 3[0,4] | |||
Facial Pain | |||||||||||||||
Mean [SD] | 2.9[1.2] | 2.8[1.6] | 2.9[1.2] | 3[1.1] | 2.7[1.5] | 3[1.2] | 2.8[1.3] | 3.3[1.8] | 2.9[1.4] | 2.3[1.1] | 3.5[1] | 2.5[1.2] | |||
Median [MIN, MAX] | 3.0 [1.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[1,5] | 3[0,5] | 3[0,5] | 3[1,5] | 4[0,5] | 3[0,5] | 2[1,4] | 3[3,5] | 3[1,5] | |||
Difficulty Falling Asleep | |||||||||||||||
Mean [SD] | 2.7[1.2] | 2.6[1.4] | 2.7[1.2] | 2.7[1.1] | 2.5[1.4] | 2.7[1.1] | 2.6[1.3] | 3[1.6] | 2.7[1.3] | 2.3[0.9] | 2.5[1] | 2.3[0.9] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[1,5] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 2[1,4] | 2[2,4] | 2[1,4] | |||
Waking Up At Night | |||||||||||||||
Mean [SD] | 2.6[1.2] | 2.5[1.5] | 2.5[1.2] | 2.6[1.1] | 2.5[1.4] | 2.5[1.2] | 2.5[1.3] | 2.7[1.8] | 2.6[1.4] | 2.1[1] | 2[0] | 2[0.9] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 2.5[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 2[0,5] | 2.5[0,5] | 2[1,4] | 2[2,2] | 2[1,4] | |||
Lack Of A Good Sleep | |||||||||||||||
Mean [SD] | 2.7[1.2] | 2.6[1.4] | 2.7[1.2] | 2.7[1.1] | 2.6[1.5] | 2.7[1.2] | 2.6[1.2] | 2.9[1.1] | 2.6[1.2] | 2.3[1.1] | 2.3[0.5] | 2.3[1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 2[0,5] | 3[0,5] | 3[0,5] | 3[1,4] | 3[0,5] | 2[1,4] | 2[2,3] | 2[1,4] | |||
Waking Up Tired | |||||||||||||||
Mean [SD] | 2.9[1.1] | 2.6[1.3] | 2.8[1.1] | 3[1] | 2.5[1.4] | 2.9[1.1] | 2.8[1.2] | 2.7[1] | 2.8[1.2] | 2.4[1.1] | 2.3[0.5] | 2.3[1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 3[1,4] | 3[0,5] | 2[1,4] | 2[2,3] | 2[1,4] | |||
Fatigue During The Day | |||||||||||||||
Mean [SD] | 2.9[1.1] | 2.7[1.2] | 2.9[1.1] | 3[1] | 2.7[1.2] | 2.9[1.1] | 2.9[1.2] | 2.7[1] | 2.9[1.1] | 2.3[1.2] | 2.3[0.5] | 2.3[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [1.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[1,5] | 3[0,5] | 3[0,5] | 3[1,4] | 3[0,5] | 2[1,5] | 2[2,3] | 2[1,5] | |||
Reduced Productivity | |||||||||||||||
Mean [SD] | 3.0[1.1] | 2.9[1.4] | 3.0[1.1] | 3.1[1] | 2.9[1.5] | 3[1.1] | 2.7[1.2] | 2.3[0.5] | 2.6[1.1] | 2.7[1.2] | 2.3[0.5] | 2.6[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 4[0,5] | 3[0,5] | 3[1,5] | 2[2,3] | 2[1,5] | 3[1,5] | 2[2,3] | 2[1,5] | |||
Reduced Concentration | |||||||||||||||
Mean [SD] | 2.9[1.2] | 2.9[1.3] | 2.9[1.2] | 3[1.2] | 2.8[1.4] | 3[1.2] | 2.7[1.2] | 3[1.2] | 2.8[1.2] | 2.9[1.4] | 2.8[1] | 2.9[1.3] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 3[1,5] | 3[0,5] | 3[1,5] | 2.5[2,4] | 3[1,5] | |||
Frustated Restless Irrtable | |||||||||||||||
Mean [SD] | 2.9[1.1] | 2.9[1.6] | 2.9[1.2] | 3[1.1] | 2.8[1.6] | 2.9[1.2] | 2.9[1.1] | 3.1[1.6] | 3[1.2] | 2.6[1.1] | 2.8[1.5] | 2.6[1.2] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[1,5] | 3[0,5] | 3[0,5] | 3[0,5] | 3[1,5] | 3[0,5] | 3[1,5] | 2[2,5] | 2[1,5] | |||
Sad | |||||||||||||||
Mean [SD] | 2.8[1.1] | 2.7[1.6] | 2.8[1.2] | 2.8[1.1] | 2.6[1.5] | 2.8[1.2] | 2.8[1.1] | 3.1[1.9] | 2.9[1.2] | 2.4[1] | 2.8[1.5] | 2.4[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 3[0,5] | 3[0,5] | 3[0,5] | 4[0,5] | 3[0,5] | 2[1,5] | 2[2,5] | 2[1,5] | |||
Embrrassed | |||||||||||||||
Mean [SD] | 2.6[1.1] | 2.4[1.5] | 2.6[1.2] | 2.6[1.1] | 2.2[1.4] | 2.6[1.1] | 2.6[1.2] | 3[1.7] | 2.7[1.3] | 2.6[1.2] | 2[0] | 2.5[1.1] | |||
Median [MIN, MAX] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3.0 [0.0,5.0] | 3[0,5] | 2[0,5] | 3[0,5] | 3[0,5] | 4[0,5] | 3[0,5] | 3[1,5] | 2[2,2] | 2[1,5] | |||
SNOT-22 score | P < 0.001 | P < 0.001 | P < 0.001 | ||||||||||||
Mean [SD] | 65.3[16.4] | 56.4[20.0] | 63.7[17.4] | 66.3[14.6] | 54.7[19.6] | 64.1[16.2] | 63.9[17.9] | 62.9[18.3] | 63.7[17.8] | 59.1[14.7] | 65[1.6] | 60.2[13.3] | |||
Median [MIN, MAX] | 68.0 [3.0,95.0] | 69.0 [15.0,83.0] | 67.0 [3.0,95.0] | 69[19,95] | 62[23,83] | 67[19,95] | 67[21,93] | 71[25,78] | 67.5[21,93] | 59[35,76] | 65[63,67] | 65[35,76] |