Skip to main content
. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Adv Biosyst. 2020 May 18;4(6):e2000049. doi: 10.1002/adbi.202000049

Figure 4. MDSC cell migration in MDSC–PyMT cancer cell polydispersed on patterned PDMS co-culture and compartmentalized co-culture.

Figure 4.

MSC2 cell migration tracks at 12 hours under (a) poly-dispersed co-culture on textured PDMS, and (b) compartmentalized co-culture on TCPS. In polydispersed culture, the presence of Py230 cells leads to a significant increase in (c) accumulated distance and (d) Euclidean distance, while no change is observed in the presence of Py8119 cells. In the compartmentalized configuration, a significant increase in (e) accumulated distance is noted for MSC2 cells in the presence of Py230 cells, but not with Py8119 cells. (f) The Euclidean distance of MSC2 cells drops significantly in the presence of Py8119 cells. One Way ANOVA on ranks was used to establish p-value. (n=3 samples, 60–100 cells per group), scale bar =100μm.