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. 2020 Sep 14;128(9):095002. doi: 10.1289/EHP6980

Figure 3.

Figure 3 is a tabular representation of International Agency for Research on Cancer Monographs criteria for evidence synthesis, having four columns, namely, Evidence of cancer in humans, Evidence of cancer in experimental animals, Mechanistic evidence, and Evaluation. Row 1: Sufficient and Carcinogenic (Group 1). Row 2: Sufficient; Strong (exposed humans); and Carcinogenic (Group 1). Row 3: Limited; Sufficient; and Probably carcinogenic (Group 2 A). Row 4: Limited; Strong; and Probably carcinogenic (Group 2 A). Row 5: Sufficient; Strong (human cells or tissues); and Probably carcinogenic (Group 2 A). Row 6: Strong (mechanistic class) and Probably carcinogenic (Group 2 A). Row 7: Limited and Probably carcinogenic (Group 2 B). Row 8: Sufficient and Probably carcinogenic (Group 2 B). Row 9: Strong (experimental systems) and Probably carcinogenic (Group 2 B). Row 10: Sufficient; Strong (does not operate in humans); and Not classifiable (Group 3). Row 11: All other situations not listed here and Not classifiable (Group 3).

IARC Monographs criteria for evidence synthesis. Adapted from IARC (2019b).