Figure 2. Immune Phenotype in Psoriasis Distilled to the Expression of 33 Genes.
A, An analysis of nonlesional phenotype and lesional phenotype among just psoriasis lesions shows similar immune cells to the analysis including both psoriatic lesional and nonlesional samples in Figure 1A. Shown is unsupervised clustering of immune cells for 85 psoriasis lesions (Pso-L) samples in the GSE30999 as a training cohort. B, DEGs indicates differentially expressed genes. Flowchart of the method to determine the final 33-gene set that defines the psoriatic microenvironment.