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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Cancer Res. 2020 Apr 8;80(11):2114–2124. doi: 10.1158/0008-5472.CAN-19-2918

Figure 5. Hispanic/Latino gastric cancer patients have high rates of germline CDH1 mutations.

Figure 5.

a. Seven germline CDH1 mutations were identified in patients with diffuse gastric cancer.

b. Western blot showing E-cadherin expression level upon transfection of plasmids carrying wild-type CDH1, A286G variant, or G1849A variant into Chinese hamster ovary cells.

c. Representative pictures of scratch assays. Distance between the wound edges were measured after 24 hours.

d. Quantification of remaining distance between wound edges, relative to 0h. N ≥ 9 per group, with at least two independent experiments. ** P < 0.01, *** P < 0.001, **** P < 0.0001