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. 2020 Sep 14;15(9):e0239233. doi: 10.1371/journal.pone.0239233

Table 1. Characteristics of the included RCT studies.

Author (year) Journal Location Medication Type of patient Primary endpoint No. of eyes Sex (male/female) Age
Glaucoma NSAID NSAID Control NSAID Control
C. Costagliola (2005) Exp Eye Res Italy Timolol/ Latanoprost Diclofenac POAGa 10 weeks 32 32 16/16 16/16 55.4±5.11
T. Chiba (2006) Br J Ophthalmol Japan Latanoprost Bromfenac POAG/ OHb 18 weeks 13 13 6/7 6/7 65.2±8.8
C. Costagliola (2008) Curr Eye Res Italy Latanoprost Ketorolac POAG 1 day 16 16 9/7 9/7 59.45±4.55
R. Sorkhabi (2011) J Glaucoma Iran Latanoprost Diclofenac POAG 2 weeks 22 22 12/10 12/10 60.55±9.46
E. Turan-Vural (2011) Ophthalmologica Turkey Latanoprost/Travoprost/ Brimatoprost Ketorolac POAG/ Pseudo-exfoliation glaucoma 2 weeks 30 30 15/15 15/15 60.8±11.5
P. Özyol (2016) J Glaucoma Turkey Latanoprost/ Travoprost/ Brimatoprost Nepafenac POAG 2 weeks 35 35 20/15 20/15 60.28±7.51
Z. Simin (2018) J Ophthalmol China Latanoprost Pranoprofen POAG 10weeks 24 24 13/11 10/14 32.4±4.7

aPOAG = primary open angle glaucoma

bOH = ocular hypertension