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. 2020 Sep 11;5(3):e20.00031. doi: 10.2106/JBJS.OA.20.00031

TABLE VII.

Predictors of Mobility Outcomes in OI Types III and IV: Rodded Group

Predictor Mobility Outcome* Conclusions
GFAQ Walking Ability Score FMS 5 m FMS 50 m FMS 500 m BAMF Lower-Extremity Gross Motor Scale
Logistic regressions: ln(P/(1 − P)) = A + B × X
 OI Type III or IV vs. OI Type I 10.2 2.2 4.4 5.7 5.7 OI Types III and IV showed worse mobility outcome compared with OI Type I
 Non-expanding vs. expanding rods in tibiae 3.6§ NS 4.4 3.6§ 2.9 Subjects with non-expanding rods in tibiae showed worse results than those with expanding rods
 Non-expanding vs. expanding rods in femora NS NS NS NS NS No significant differences in mobility outcome for subjects with expanding or non-expanding rods in femora
 Bisphosphonates: no or yes NS NS NS NS NS No significant differences in mobility outcome for rodded subjects with or without treatment with oral or intravenous bisphosphonates
 Simultaneous rodding of both femora vs. 1 femur NS NS NS NS NS No significant differences in mobility outcome for subjects with simultaneous or non-simultaneous femoral rodding
 Simultaneous rodding of femur and tibia vs. 1 femur 6.5 3.9 6.4 4.1 6.3 Subjects with tibiae and femora rodded simultaneously had significantly worse mobility outcome
 Sequence of rodding: 2 femora vs. 1 femur first NS NS NS NS NS No significant differences in mobility outcome for subjects with 1 femoral rodding first compared with 2 femora first
Linear regressions: Y = A + B × X
 Standardized height 0.22 0.18 0.21 0.13 0.21 A weak association was found between standard height and all of the mobility outcome (direct relation)
 Standardized weight 0.10 0.07 0.10 0.07 0.08 A weak association was found between standard weight and all of the mobility outcomes (direct relation)
 Standardized BMI 0.11 0.05 0.06 0.06 0.10 A weak association was found between standard BMI and all of the mobility outcomes (direct relation)
 Age at first rodding NS NS NS NS NS No association was found between the age at the time of the first rodding surgical procedure reported and the mobility outcome
*

NS = no significant correlation.

The values are given as the odds ratio for the logistic regression or as the coefficient of determination (R2) for the linear regression.

Significant at p ≤ 0.05.

§

Significant at p ≤ 0.01.