Before COVID-19 estimates from the National Health and Nutrition Examination Survey (NHANES) from 2017-2018. During COVID-19 estimates from the COVID-19 and Life Stressors Impact on Mental Health and Well-being (CLIMB) study collected from March 31 to April 13, 2020. Depression symptoms categories calculated using the Patient Health Questionnaire–9: none (0-4), mild (5-9), moderate (10-14), moderately severe (15-19), and severe (≥20). Percentages weighted to the population of noninstitutionalized US adults aged 18 years or older.