Table 1. Frequency of Presenting Symptoms Among the BRIGHTLIGHT Cohort.

Symptom	Patients, No. (%) [95% CI] (N = 803)a
Lump or swelling	419 (52) [49-56]
Extreme tiredness	308 (38) [35-42]
Unexplained pain	281 (34) [32-38]
Night sweats	192 (24) [21-27]
Lymphadenopathy	191 (24) [21-27]
Weight loss	190 (24) [21-27]
Headaches	127 (16) [13-19]
Dizziness	126 (16) [13-18]
Rash or itching	94 (12) [10-14]
Limping or mobility problems	77 (10) [8-12]
Bruising or bleeding	73 (9) [7-11]
Other symptomsb	69 (9) [7-11]
Menstrual changes	56 (7) [5-9]
Recurrent infections	47 (6) [4-8]
Mole changes	40 (5) [4-7]
Loss of vision	27 (3) [2-5]
Fits or seizures	17 (2) [1-3]

^aTotal sum exceeds 803 (100%) because patients could report multiple symptoms.

^bOther symptoms include symptoms with less than 2% frequency (see eTable 1 in the Supplement).