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. 2020 Sep 8;324(10):961ā€“974. doi: 10.1001/jama.2020.8958

Figure 2. Post Hoc Descriptive Analysis of Mortality Through 28 Days in a Study of the Effect of Tranexamic Acid vs Placebo on Neurologic Outcomes in Patients With Traumatic Brain Injury.

Figure 2.

Survival data to 28 days was available for 91% of participants in the bolus maintenance group, 92% in the bolus only group, and 92% in the placebo group. Participants who were lost to follow-up after discharge or study withdrawal prior to 28 days and who were notified themselves about their study enrollment rather than family member notification were assumed to survive through 28 days for this plot (nā€‰=ā€‰52). The remaining participants were censored before 28 days: 5 [2%] in the bolus maintenance group, 9 [3%] in the bolus only group, and 12 [4%] in the placebo group. The shaded areas represent pointwise 95% CIs for each treatment group. The median (interquartile range) observation time for all 3 groups was 28 (28-28) days.