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. 2020 Sep 10;477(17):3253–3269. doi: 10.1042/BCJ20200520

Figure 2. Overview of the structures of importin α bound with ChREBP NLS 158–190.

Figure 2.

(A) Ribbon diagram of the ChREBP-NLS peptide (pink) bound to importin α. (B) Major interactions between ChREBP NLS 158–190 and importin α. P2–P5 pockets of importin α were occupied by K171–I174 of ChREBP NLS 158–190, and the interacting residues of importin α are all shown. (C) Close-up view of ChREBP NLS 158–190 in the active site of importin α with omit map (Fo–Fc) contoured at 3σ around ChREBP peptide. (D) Close-up view of ChREBP NLS 158–190 in the active site of importin α with electro density map (2Fo–Fc) contoured at 1σ around ChREBP peptide.