Table 4. Comparison of nuclear localization sequences.
NLS | Sequence | KD (µM) (Ref.) |
---|---|---|
ChREBP 158–190 | R158KPEAVVLEGNYWKRRIEVVMREYHKWRIYYKK190 | 3.03 ± 0.95 [5] |
Nucleoplasmin | K155RPAATKKAGQAKKKK170 | 0.19 ± 0.02 [23] |
SV40 | P126KKKRKV132 | 0.31 ± 0.15 [26] |
AR | R617KCYEAGMTLGARKLKKL634 | 5 ± 0.1 [22] |
Key basic residues of NLS for the major binding site are presented in red. The KD value of ChREBP-NLS — importin α was determined with ITC measurement.