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. 2020 Jul 21;295(37):12851–12867. doi: 10.1074/jbc.RA120.013636

Table 3.

GTP analogs, substituted group at the 2′ position and properties associated with these groups

S. No. GTP analogs Group at 2′ position Property conferred
1 GTP OH 3′-Endo conformation
2 dGTP H 3′-Exo conformation
3 2′-F dGTP F 3′-Endo conformation
4 2′-NH2 dGTP NH2 Can accept and donate H-bond
5 2′-O-Me dGTP O-CH3 Can accept H-bond but cannot transfer proton