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. 2020 Sep 9;12:8253–8261. doi: 10.2147/CMAR.S251881

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© 2020 Yao et al.

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GAS5 knockdown promoted OS cell proliferation, migration, and invasion.

Notes: (A) GAS5 expression in OS cells transduced with si-GAS5 and si-NC. (B) Cell proliferation assay indicated that cell viability was stimulated after knockdown of GAS5. (C) Wound-healing assay showed the cell migration distance was increased by si-GAS5. (D) Transwell invasion assay revealed that cell invasion numbers in OS cells were enhanced by si-GAS5. ***P < 0.001, **P < 0.01.

Abbreviations: GAS5, growth arrest specific 5; OD, optical density; OS, osteosarcoma; si-GAS5, small interfering RNA against GAS5; si-NC, negative control small interfering RNA.