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. Author manuscript; available in PMC: 2020 Sep 14.
Published in final edited form as: Crit Care Med. 2019 Aug;47(8):1125–1134. doi: 10.1097/CCM.0000000000003848

TABLE 1.

Comparison of Odds Ratios and Area Under Receiver Operating Characteristic Curve (AUC) Across Time at ICP Levels for Mortality and Poor mRS (46) at Days 30 and 180

ICP Threshold (mm Hg) Odds Ratio (95% CI) p AUC Correctly Classified (%)

Day 30 Mortality
 >10 1.12 (0.97–1.30) 0.11 0.828 88.45
 >15 1.14 (0.98–1.33) 0.09 0.825 88.67
 >18 1.27 (1.03–1.57) 0.02 0.826 89.98
 >20 1.48 (1.15–1.90) 0.002 0.828 90.20
 >22 1.63 (1.20–2.22) 0.002 0.828 90.63
 >25 2.09 (1.38–3.15) <0.001 0.831 90.20
 >30 2.47 (1.33–4.59) 0.004 0.832 89.54
 >20 in spans 1.77 (1.22–2.58) 0.003 0.838 88.67
Day 180 Mortality
 >10 1.04 (0.94 – 1.14) 0.48 0.772 81.28
 >15 1.08 (0.96–1.21) 0.19 0.772 82.16
 >18 1.15 (0.98–1.35) 0.09 0.772 83.04
 >20 1.21 (0.99–1.49) 0.06 0.772 82.60
 >22 1.26 (0.98–1.62) 0.08 0.772 82.60
 >25 1.34 (0.95–1.88) 0.09 0.771 81.50
 >30 1.42 (0.84–2.39) 0.19 0.773 81.72
 >20 in spans 1.43 (1.03–1.99) 0.03 0.785 83.44
Day 30 Poor mRS
 >10 1.06 (0.94–1.20) 0.34 0.895 86.75
 >15 1.07 (0.94–1.22) 0.33 0.895 86.75
 >18 1.11 (0.92–1.35) 0.27 0.895 86.98
 >20 1.17 (0.89–1.53) 0.27 0.895 86.75
 >22 1.12 (0.62–1.30) 0.55 0.894 86.98
 >25 1.10 (0.65–1.88) 0.71 0.893 86.98
 >30 0.85 (0.37–1.96) 0.71 0.895 86.75
 >20 in spans 1.55 (0.92–2.62) 0.10 0.899 87.42
Day 180 Poor mRS
 >10 0.99 (0.90–1.09) 0.90 0.854 77.11
 >15 1.08 (0.97–1.20) 0.16 0.856 78.00
 >18 1.11 (0.96–1.27) 0.16 0.856 78.44
 >20 1.14 (0.95–1.37) 0.16 0.856 78.22
 >22 1.11 (0.88–1.40) 0.39 0.855 77.78
 >25 1.07 (0.77–1.49) 0.70 0.854 77.78
 >30 1.12 (0.65–1.93) 0.68 0.854 77.56
 >20 in spans 1.21 (0.91–1.60) 0.19 0.855 78.22

CPP = cerebral perfusion pressure, ICP = intracranial pressure. All models adjusted for number of ICP/CPP readings per patient, age, Glasgow Coma Scale, intracerebral hemorrhage (ICH) and intraventricular hemorrhage volume, thalamic ICH location, treatment group, and admission systolic blood pressure.