Table 4.

Univariate and multivariate analyses of risk factors for progression of pancreatic cystic lesions

Risk factors	Progression vs. stable				<30 mm and without high-risk characteristics vs. ≥30 mm or with high-risk characteristics
	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	OR	P	OR	P	OR	P	OR	P
Age	1.033 (1.003, 1.064)	0.029	1.042 (1.007, 1.078)	0.017	1.045 (0.988, 1.106)	0.122
Sex
Male	1.465 (0.850, 2.525)	0.170			0.831 (0.318, 2.170)	0.705
Female	1				1
Initial size	1.082 (1.036, 1.130)	<0.001	1.028 (0.969, 1.089)	0.362	1.313 (1.160, 1.486)	<0.001	1.346 (1.117, 1.540)	<0.001
Morphology
Rounded	0.359 (0.203, 0.633)	<0.001	0.991 (0.444, 2.210)	0.982	0.347 (0.125, 0.965)	0.043	1.182 (0.265, 5.273)	0.826
Not rounded	1		1		1		1
Number
Single	0.506 (0.281, 0.911)	0.023	0.491 (0.243, 0.992)	0.048	2.105 (0.729, 6.075)	0.169
Multiple	1		1		1
Communication to PD
Present	3.915 (2.206, 6.949)	<0.001	2.425 (1.269, 4.634)	0.007	4.630 (1.241, 17.268)	0.023	8.112 (1.604, 41.020)	0.011
Absent	1		1		1		1
Septa
Present	6.019 (3.317, 10.922)	<0.001	6.105 (3.131, 11.903)	<0.001	3.529 (1.072, 11.618)	0.038	1.452 (0.329, 6.418)	0.632
Absent	1		1		1
History of malignant tumors
Yes	0.612 (0.335, 1.120)	0.111			0.358 (0.095, 1.358)	0.131
No	1				1

Data in parentheses are 95% confidence intervals.

PD, pancreatic duct; OR, odd ratio.