Table 3.
Effect of Vitamin D in Functional Outcomes in Patients Undergoing Hip Arthroplasty
| Author | Mean Vitamin D Levela | Scores | Groups Compared | Main Clinical Findings |
|---|---|---|---|---|
| Visser et al18 | 68.1 nmol/l | WOMAC, HGS, CST, TUGT, 10-MWT, LAPAQ | D <50 ng/mL I: 50–75 ng/mL S ≥75ng/mL |
No differences in preoperative total scores between groups No differences in postoperative HGS, CST, 10-MWT, WOMAC Insufficient patients: higher postoperative LAPAQ score |
| Cuhna et al28 | 13.8 ng/mL | Gait Analysis | NA | Baseline Vitamin D levels: weak correlation with change in peak extension (p = 0.017) and peak power generation (p = 0.04) Vitamin D levels: no effect in change of gait pattern |
| Lavernia et al19 | NA | WOMAC, HHS, PMA, QWB-7, SF-36 | I <20 or 30 ng/mL S >20 or 30 ng/mL |
No differences in preoperative and postoperative total scores between groups when the threshold was set in 20 ng/mL No differences in preoperative and postoperative total scores of WOMAC, QWB-7 and SF-36 between groups when the threshold was set in 30 ng/mL Significant differences in preoperative and postoperative total scores of HHS and Merle d’Aubigne’-Postel score between groups when the threshold was set in 30 ng/mL favoring sufficient group |
| Unnanuntana et al22 | D:15.7 ng/mL I:26.7 ng/mL S:43.8 ng/mL |
Transferring in and out of bed, ability to walk with assisting devices and ability to ascend/descent stairs | I <32 ng/mL S>32 ng/mL |
No association between vitamin D level and the attainment of in hospital functional milestones |
| Nawabi et al20 | 58 nmol/l | HHS | S >40nmol/l D <40nmol/l |
Sufficient patients: significantly higher preoperative HHS (p = 0.018) Sufficient patients: non-significantly higher postoperative HHS at 6 months (p = 0.067) Deficient patients: significantly less likely to attain an excellent outcome (p = 0.038) |
| Unnanuntana et al21 | NA | WOMAC, SF-36, TUGT, Two-min walk test | S>30 ng/mL I<30 ng/mL |
No differences in preoperative scores between groups No differences in postoperative WOMAC and SF-36 between groups Deficient patients: significantly improved TUGT postoperatively |
Notes: aMean vitamin D level is given for the whole group or for separate groups accordingly.
Abbreviations: CST, Chair Stand Test; TUGT, timed up and go test; 10-MWT, 10-meter walking test; NA, non available; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; HHS, Harris Hip Score; SF-36, 36-Item Short Form Survey; HGS, hand grip strength; LAPAQ, LASA Physical Activity Questionnaire; QWB-7, Quality of Well-being Scale; 25-(OH)D3, 25-hydroxyvitamin D3; D, deficient; S, sufficient; I, insufficient; PMA, Merle d’Aubigne’-Postel.