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. 2020 Sep 7;12:8093–8103. doi: 10.2147/CMAR.S264674

Figure 2.

Figure 2

CircFLNA knockdown inhibited GC cell progression and GC tumor growth. (A-B) The transfection efficiencies of sh-circFLNA#1/#2/#3 were confirmed by detecting circFLNA expression using qRT-PCR. (C-G) HGC27 and AGS cells were transfected with sh-NC or sh-circFLNA#3. CCK8 assay (C-D), transwell assay (E-F) and flow cytometry (G) were performed to measure cell proliferation, migration, invasion and apoptosis, respectively. (H-I) AGS cells transfected with sh-NC or sh-circFLNA#3 were injected into the nude mice to build GC tumor xenograft models. Tumor volume (H) and tumor weight (I) were measured in mice. *P < 0.05, **P < 0.01, ***P < 0.001.