Table 7.
The Calculated Incremental Cost-Effectiveness Ratios When Using Colonoscopy vs FIT and FOBT
| Author/Technique | C | Q | ICER | Threshold | Optimal Strategy |
|---|---|---|---|---|---|
| Dinh23 | |||||
| Colonoscopy 10-year | 2384.3 | 15.79 | 17805 | $US 50000 | Colonoscopy 10-year was cost-effective a |
| FIT yearly | 2028.2 | 15.77 | |||
| Ladabaum24 | |||||
| Colonoscopy 10-year | 4248 | 18.746 | 443778 | $US 50000 | Colonoscopy 10-year was dominated |
| FIT 2-year | 2251 | 18.741 | |||
| Sharaf25 | |||||
| Colonoscopy 10-year | 2871 | 18.7443 | 75165 | $US 50000 | Colonoscopy 10-year was dominated |
| FOBT yearly | 2187 | 18.7352 | |||
| Wong22 | |||||
| Colonoscopy 10-year | 6911 | 15.3586 | −7490 | $US 50000 | Colonoscopy 10-year was dominant |
| G-FOBT yearly | 7845 | 15.2339 | |||
| Kingsley28 | |||||
| Colonoscopy 10-year | 2474 | 19.517 | 78818 | $US 50000 | Colonoscopy 10-year was dominated |
| FIT yearly | 1607 | 19.506 |
Notes: In this table, for each study, the first row shows the new technique that is compared with the old technique, written in the second row. The negative ICER indicates that the new technique is less costly and more effective. The positive ICERs refer to those techniques that are more costly and more effective; both numerators and denominators are positive. aBased on the context threshold.
Abbreviations: C, costs per person ($PPP); Q, QALYs (quality-adjusted life-year); ICER, incremental cost-effectiveness ratio; G-FOBT, guaiac fecal occult blood testing; FIT, fecal immunochemical testing.