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. 2020 Sep 10;12:8363–8377. doi: 10.2147/CMAR.S271021

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© 2020 Fan et al.

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Depletion of DARS-AS1 attenuates PCa tumor growth in vivo. (A) Image of excised tumor xenografts from nude mice in the sh-DARS-AS1 and sh-NC groups. (B) The volumes of tumor xenografts in the sh-DARS-AS1 and sh-NC groups were monitored weekly. (C) The weights of tumor xenografts originating from DU145 cells stably overexpressing sh-DARS-AS1 or sh-NC. (D, E) The expression levels of DARS-AS1 and miR-628-5p in tumor xenografts collected from sh-DARS-AS1 and sh-NC groups were analyzed via RT-qPCR. (F) Western blotting was used for MTDH protein quantification in the tumor xenografts collected from the sh-DARS-AS1 and sh-NC groups. **P < 0.01.