Table 4.

Effect of (E)-2-(4-methoxybenzylidene)cyclopentan-1-one (A2K10) and Diazepam on Pentylenetetrazole (Ptz)-Induced Seizure Mortality in Mice

Group	% Mortality
Saline (10 mL/kg) + Ptz (90 mg/kg)	100
A2K10 (1 mg/kg) + Ptz (90 mg/kg)	80**
A2K10 (3 mg/kg) + Ptz (90 mg/kg)	60***
A2K10 (10 mg/kg) + Ptz (90 mg/kg)	20***
Diazepam (1 mg/kg) + Ptz (90 mg/kg)	0***

Notes: % Mortality = (number of mice dead after convulsions/total number of mice used) × 100, n=5. **p<0.01, ***p<0.001 vs saline group on one-way ANOVA followed by Tukey’s post hoc test.