Table 3.

Adjusted Associations of Inflammatory Markers with Anxiety, Depression and Perceived Stress Scores

Variables	Anxiety Scores				Depression Scores				Perceived Stress Scores
	R2	Sβ	95% CI	P value	R2	Sβ	95% CI	P value	R2	Sβ	95% CI	P value
Model 1
IL-6	0.175	0.009	−0.006–0.008	0.760	0.172	0.040	−0.029–0.172	0.163	0.225	0.059	0.005–0.158	0.038
IL-8	0.176	−0.018	−0.003–0.001	0.533	0173	0.044	−0.007–0.051	0.132	0.217	−0.007	−0.025–0.020	0.812
IL-10	0.175	−0.009	−0.023–0.016	0.745	0.167	0.005	−0.265–0.314	0.866	0.217	−0.016	−0.284–0.159	0.578
CRP	0.175	−0.012	−0.009–0.006	0.682	0.197	0.105	0.090–0.301	<0.001	0.229	0.073	0.024–0.186	0.001
TNF-ɑ	0.176	0.024	−0.020–0.047	0.424	0.180	0.068	0.084–1.086	0.022	0.217	0.016	−0.280–0.488	0.595
E-selectin	0.179	0.037	0.000–0.002	0.204	0.194	0.099	0.015–0.057	<0.001	0.230	0.078	0.006–0.138	0.007
ICAM-1	0.180	0.041	0.000–0.000	0.155	0.204	0.117	0.004–0.012	<0.001	0.224	0.055	0.000–0.105	0.011
Model 2
IL-6	0.199	0.010	−0.009–0.008	0.740	0.288	0.038	−0.030–0.165	0.172	0.270	0.059	0.004–0.156	0.038
IL-8	0.200	−0.018	−0.003–0.001	0.541	0.287	0.029	−0.014–0.043	0.314	0.264	−0.015	−0.028–0.016	0.601
IL-10	0.199	−0.009	−0.022–0.016	0.754	0.286	0.010	−0.230–0.334	0.716	0.264	−0.013	−0.269–0.169	0.656
CRP	0.199	−0.011	−0.008–0.006	0.713	0.302	0.098	0.079–0.284	<0.001	0.272	0.070	0.021–0.181	0.002
TNF-ɑ	0.201	0.027	−0.018–0.049	0.360	0.294	0.072	0.139–1.114	0.042	0.264	0.020	−0.247–0.513	0.493
E-selectin	0.202	0.037	0.000–0.002	0.202	0.294	0.070	0.005–0.046	<0.001	0.270	0.061	0.011–0.133	0.009
ICAM-1	0.202	0.040	0.000–0.000	0.180	0.295	0.074	0.001–0.009	<0.001	0.265	0.027	0.002–0.085	0.019
Model 3
IL-6	0.199	0.010	−0.005–0.008	0.718	0.307	0.030	−0.044–0.151	0.279	0.288	0.051	−0.006–0.145	0.072
IL-8	0.200	−0.018	−0.003–0.001	0.530	0.307	0.034	−0.011–0.045	0.232	0.284	−0.010	−0.026–0.018	0.727
IL-10	0.199	−0.009	−0.023–0.016	0.746	0.306	0.014	−0.211–0.350	0.626	0.284	−0.009	−0.255–0.181	0.741
CRP	0.199	−0.008	−0.009–0.007	0.796	0.312	0.068	0.018–0.236	<0.001	0.286	0.067	0.020–0.139	0.009
TNF-ɑ	0.201	0.029	−0.017–0.051	0.332	0.311	0.059	0.021–1.000	0.069	0.284	0.006	−0.342–0.420	0.841
E-selectin	0.203	0.041	0.000–0.002	0.167	0.309	0.049	−0.003–0.038	<0.001	0.286	0.040	0.015–0.117	0.014
ICAM-1	0.203	0.041	0.000–0.000	0.168	0.312	0.064	0.001–0.008	<0.001	0.284	0.017	0.001–0.074	0.022

Notes: Model 1: Adjusted for age and gender. Model 2: Adjusted for age, gender, race, education, marital status, smoking status, drink alcohol and BP. Model 3: Adjusted for age, gender, race, education, marital status, smoking status, drink alcohol, BP and medications.

Abbreviations: IL, interleukin; TNF-ɑ, tumor necrosis factor-ɑ; ICAM-1, intercellular adhesion molecule-1; BP, blood pressure.