Table 3.
Comparison of the α-diversity found on intraparenchymal intracranial pressure transducer (ICPT), according to different variables
| ICPTs | Richness | Evenness | |||||
|---|---|---|---|---|---|---|---|
| n = 38 | Chao 1 | p | Simpson | p | PielouE | p | |
| Location of placement | |||||||
| Operating room | 14 | 14.5 (14–19.25) | 0.36 | 0.82 (0.77–0.83) | 0.04 | 0.78 (0.73–0.79) | 0.01 |
| ICU | 24 | 17.5 (15.5–19) | 0.86 (0.83–0.89) | 0.84 (0.79–0.85) | |||
| Antimicrobial prophylaxis | |||||||
| Yes | 17 | 16 ()14–20) | 0.8 | 0.83 (0.78–0.85) | 0.05 | 0.78 (0.75–0.80) | 0.006 |
| No | 21 | 17 (14–19)) | 0.87 (0.82–0.89) | 0.84 (0.80–0.86) | |||
| Breaking of the BBB | |||||||
| Yes | 23 | 16 (14–18.5) | 0.31 | 0.83 (0.80–0.87) | 0.23 | 0.8 (0.75–0.84) | 0.28 |
| No | 15 | 18 (16–19) | 0.87 (0.83–0.88) | 0.84 (0.77–0.85) | |||
| Treatment of increased ICP | |||||||
| EVD | |||||||
| Yes | 4 | 17 (13.5–20) | 0.96 | 0.82 (0.79–0.84) | 0.23 | 0.75 (0.74–0.78) | 0.32 |
| No | 34 | 16.5 (14–18.75) | 0.85 (0.81–0.89) | 0.81 (0.77–0.85) | |||
| Hypothermia | |||||||
| Yes | 12 | 16 (13.5–19.25) | 0.52 | 0.83 (0.78–0.87) | 0.29 | 0.77 (0.74–0.86) | 0.59 |
| No | 26 | 17 (14–18.75) | 0.85 (0.82–0.89) | 0.81 (0.78–0.84) | |||
| Curarization | |||||||
| Yes | 13 | 16 (14–19) | 0.64 | 0.83 (0.78–0.87) | 0.35 | 0.78 (0.74–0.86) | 0.84 |
| No | 25 | 17 (14–19) | 0.85 (0.82–0.89) | 0.81 (0.77–0.84) | |||
| Phenobarbital | |||||||
| Yes | 8 | 16 (14–19.25) | 0.93 | 0.85 (0.80–0.87) | 0.52 | 0.78 (0.73–0.86) | 0.86 |
| No | 30 | 17 (14–18.75) | 0.85 (0.81–0.89) | 0.80 (0.77–0.84) | |||
| Antimicrobial treatment | |||||||
| Yes | 7 | 16 (14.5–19.5) | 0.85 | 0.81 (0.67–0.83) | 0.02 | 0.73 (0.62–0.77) | 0.01 |
| No | 31 | 17 (14.5–18.5) | 0.86 (0.82–0.89) | 0.82 (0.78–0.85) | |||
| Monitoring duration | |||||||
| ≤ 5 days | 25 | 17 (14–19) | 0.64 | 0.86 (0.82–0.89) | 0.26 | 0.82 (0.77–0.85) | 0.11 |
| > 5 days | 13 | 16 (15–19) | 0.83 (0.78–0.88) | 0.78 (0.73–0.84) | |||
| Mature biofilm (SEM) | |||||||
| Yes | 26 | 16.5 (14–19) | 0.96 | 0.83 (0.81–0.87) | 0.19 | 0.80 (0.75–0.84) | 0.19 |
| No | 12 | 16.5 (14.75–18.25) | 0.87 (0.82–0.89) | 0.84 (0.79–0.86) | |||
Antimicrobial prophylaxis means that ICPT was placed under surgical antimicrobial prophylaxis. Breaking of the BBB means skull depression fracture, skull base fracture, or brain surgery
BBB blood brain barrier, EVD external ventricular drain, ICPT intraparenchymal intracranial pressure transducer, ICU intensive care unit, OTU operational taxonomic units, TBI traumatic brain injury
Data are shown as the median (25th–75th percentile) or number (%), unless otherwise indicated
Significant p-values are shown in bold