Table 1. Clinical characteristics of 4 leptospirosis patients.

Patient No.	Sex	Age, yr	Time between onset of symptoms and hospital admission, day	Time between onset of symptoms and antibiotic treatment, day	Antibiotics	Time between onset of symptoms and specimen sampling, day	Specimen type	PCR,16s N-PCR	PHA
1	F	70	4	4	Ceftriaxone	4	Plasma	Negative	1:1,280
					Doxycycline	9	Urine	Positive	1:20,480
						13	CSF	Positive
						15	Urine	Positive
						15	Plasma	Negative
						16	Buffy coat	Negative
						16	Plasma	Negative
						18	Buffy coat	Negative
						18	Urine	Positive
						18
2	F	73	6	11	Doxycycline	6	Buffy coat	Negative	Negative
						10	Urine	Positive	1:5,120
						10	Plasma	Positive
						10
						11
3	F	80	6	6	Doxycycline	6	Plasma	Negative	Negative
						8	Urine	Positive	1:10,240
						8	CSF	Positive
						8	Buffy coat	Negative
						12
4	F	76	4	4	Doxycycline	5	Plasma	Positive	Negative
						6	Buffy coat	Negative	1:1,280
						7
						10

PCR = polymerase chain reaction, PHA = passive hemagglutination assay.