Table 2.

POAG Validation Results in an Independent UK Biobank Sample

SNP	Pos	Locus	A1	Info	Freq Controls	Freq Cases	OR	Effect	SE	P Value
rs2107482	3282064	MXRA5	G	0.986	0.317	0.308	0.974	−0.026	0.019	0.16
rs66819623	13954397	GPM6B	C	0.975	0.573	0.546	0.926	−0.077	0.018	1.2 × 10−5
rs12558081	43939978	NDP/EFHC2	A	0.994	0.697	0.684	0.960	−0.041	0.019	0.029

‘SNP’ is the variant rsid, ‘Pos’ is the base pair position (Human genome build 37), ‘Locus’ is the nearest gene/s to the SNP, ‘A1’ is the reference allele, ‘Info’ is a imputation quality score (scale 0-1), ‘Freq controls’ is the A1 allele frequency in the controls and ‘Freq cases’ is the A1 allele frequency in POAG cases in the UK Biobank cohort for this analysis, ‘OR’ is the odds ratio for A1, ‘Effect’ and ‘SE’ are the natural logarithm of OR and the respective standard error, ‘P’ is the respective association P value.