Table 3.

IOPcc Sex-Stratified Results

			Men						All Women						Homozygous Women
SNP	Locus	A1	N	Freq	Beta	SE	95% CI	P Value	N	Freq	Beta	SE	95% CI	P Value	N	Freq	Beta	SE	95% CI	P Value
rs2107482	MXRA5	G	48015	0.317	−0.098	0.017	−0.065 −0.129	1.9 × 10−8	54392	0.315	−0.073	0.021	−0.032 −0.114	7.5 × 10−4	31328	0.180	−0.093	0.025	−0.044 −0.142	1.7 × 10−4
rs66819623	GPM6B	C	48015	0.572	−0.086	0.016	−0.055 −0.117	4.2 × 10−8	54392	0.571	−0.045	0.020	−0.006 −0.084	0.017	28775	0.635	−0.046	0.021	−0.005 −0.087	0.028
rs12558081	NDP/EFHC2	A	48015	0.696	−0.092	0.017	−0.059 −0.125	1.4 × 10−7	54392	0.698	−0.084	0.022	−0.041 −0.127	1.5 × 10−4	31324	0.844	−0.068	0.026	−0.017 −0.119	8.8 × 10−3

‘SNP’ is the variant rsid, ‘Locus’ is the nearest gene/s to the SNP, ‘A1’ is the reference allele, ‘Freq’ is the A1 allele frequency for each subgroup in this analysis, ‘Beta’ and ‘SE’ are the linear regression coefficients and respective standard errors for the A1 allele in the respective sample, ‘95% CI’ is the 95% confidence interval for the Beta, ‘P’ is the respective association P value in each sample, ‘N’ is the respective sample size of each sample. The homozygous female sample is defined by female participants that are homozygous for the tested SNP on each row.