Table 1.
Somy estimation in RepliG and PicoPLEX BPK275 samples, without and with GC bias correction. ASD (average somy deviation) between a sample derived from the respective cell number (ranging from 1,000 to 10) and BPK275 control and corresponding standard deviation.
| Cell | Without GC correction | With GC correction | ||||
|---|---|---|---|---|---|---|
| ASD | std | SDC | ASD | std | SDC | |
| RepliG_1000 | 0.73 | 0.50 | 20 | 0.42 | 0.31 | 13 |
| RepliG_100 | 0.88 | 0.59 | 21 | 0.57 | 0.38 | 18 |
| RepliG_50 | 0.99 | 0.59 | 28 | 0.59 | 0.40 | 19 |
| RepliG_25 | 1.06 | 0.76 | 27 | 0.64 | 0.52 | 18 |
| PicoPLEX_1000 | 0.28 | 0.30 | 4 | 0.30 | 0.26 | 8 |
| PicoPLEX_100 | 0.30 | 0.31 | 7 | 0.29 | 0.25 | 7 |
| PicoPLEX_50 | 0.26 | 0.26 | 5 | 0.16 | 0.16 | 2 |
| PicoPLEX_25 | 0.32 | 0.31 | 6 | 0.21 | 0.19 | 3 |
| PicoPLEX_10 | 0.62 | 0.56 | 20 | 0.42 | 0.36 | 11 |
| ave_RepliG | 0.92 | 0.61 | 24.00 | 0.56 | 0.40 | 17.00 |
| ave_PicoPLEX | 0.36 | 0.35 | 8.40 | 0.28 | 0.24 | 6.20 |
For somy difference count (SDC), we counted in each sample the number of chromosomes showing a somy value difference > 0.5 in comparison to BPK275 control. The average values were summarized at the bottom of the table.